30359-01-4

Basic information

• Product Name: Centrolobol
• Synonyms: (R)-(-)-1,7-Bis(p-hydroxyphenyl)-3-heptanol;Centrolobol
• CAS NO: 30359-01-4
• Molecular Formula: C₁₉H₂₄O₃
• Molecular Weight: 300.39206
• Mol File: 30359-01-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Centrolobol(CAS DataBase Reference)
• NIST Chemistry Reference: Centrolobol(30359-01-4)
• EPA Substance Registry System: Centrolobol(30359-01-4)

Safety Data

• Hazardous Substances Data: 30359-01-4(Hazardous Substances Data)

Usage

General Description

Centrolobol is a natural compound found in the stem bark of Centrolobium ochroxylum, a plant native to South America. It belongs to the group of compounds known as 3-benzylcoumarins and has been the subject of research for its potential medicinal properties. Studies have shown that centrolobol exhibits anti-inflammatory, anti-tumor, and anti-fungal activities, making it an interesting candidate for the development of new drugs. Its chemical structure and biological effects have sparked interest in the scientific community, and further research is ongoing to explore its potential applications in medicine.

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Downstream Products

• 130233-83-9 1,7-bis(4'-hydroxyphenyl)-3-heptanone 

Relevant articles and documents

Absolute Configuration of Platyphylloside and (-)-Centrolobol

The ansolute configuration of platyphylloside was established to be S by 13C NMR spectroscopy.On the basis of this establishment, the S-configuration previously assigned to the chirality at C-3 of (-)-centrolobol was revised to the R-configuration.

Identification of centrolobol as the platyphylloside metabolite responsible for the observed effect on in vitro digestibility of hay

Syntheses of the metabolites from platyphylloside, a phenol causing digestibility inhibition in rumen fluid, have been performed to identify the active metabolite. 1,7-Bis(4′-hydroxyphenyl)-3-heptanone (3-platyphyllone), racemic, and the two enantiomers o