30432-65-6

Basic information

• Product Name: N-ethyl-N-(α-methylbenzyl)aniline
• Synonyms: N-ethyl-N-(α-methylbenzyl)aniline
• CAS NO: 30432-65-6
• Molecular Weight: 225.334
• Mol File: 30432-65-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-ethyl-N-(α-methylbenzyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-N-(α-methylbenzyl)aniline(30432-65-6)
• EPA Substance Registry System: N-ethyl-N-(α-methylbenzyl)aniline(30432-65-6)

Safety Data

• Hazardous Substances Data: 30432-65-6(Hazardous Substances Data)

Upstream product

• 98-85-1 1-Phenylethanol 
• 103-69-5 N-ethyl-N-phenylamine 
• 57818-33-4 N-ethyl-N-(1-phenylethenyl)aniline 
• 536-74-3 phenylacetylene 
• 129575-56-0 (R)-α-methylbenzyl azide 
• 32366-25-9 1-azidoethylbenzene 
• 25236-63-9 1-phenylethyl mesylate 
• 91-66-7 N,N-diethylaniline 
• 538-51-2 benzylidene phenylamine 
• 82769-48-0 N-ethyl-N-(1-methoxyethyl)aniline 
• 779-54-4 phenyl(1-phenylethyl)amine 
• 368-39-8 triethyloxonium fluoroborate 
• 672-65-1 (1-chloroethyl)benzene 

Relevant articles and documents

Achieving Aliphatic Amine Addition to Arylalkynes via the Lewis Acid Assisted Triazole-Gold (TA-Au) Catalyst System

Transition metal catalyzed intermolecular hydroamination of the arylalkynes with aliphatic amine is generally problematic due to the good coordination between amine and metal cation. With the combination of 1,2,3-triazole coordinated gold(I) catalyst (TA-Au) and Zn(OTf)2 cocatalyst, this challenging transformation was achieved with good to excellent yields and regioselectivity. Compared to previously reported methods, this approach offered an alternative catalyst system to achieve this fundamental chemical transformation with high efficiency and practical conditions.

Tin-Catalyzed Selective Reductive Hydroamination of Alkynes for the Synthesis of Tertiary Amines

A unique preference of tin(II) for aniline activation is disclosed. In the present work tin(II) triflate-catalyzed highly selective Markovnikov reductive hydroamination of internal as well as terminal alkynes is reported. The mechanistic study revealed the involvement of two steps in one pot wherein alkyne reduces to corresponding alkene in presence of PMHS as reducing agent followed by hydroamination of alkene. A broad range of alkynes transformed into tertiary amines with good to excellent yield. This method is equally applicable in synthesis of secondary amines.

A Lewis acid mediated schmidt reaction of benzylic azide: Synthesis of sterically crowded aromatic tertiary amines

An efficient one-pot synthesis of sterically hindered aromatic tertiary amines through Lewis acid induced intermolecular Schmidt reaction of benzylic azides is described. In the presence of EtAlCl2, benzylic azide underwent a smooth Schmidt reaction to give the corresponding iminium ion, which, upon reduction with NaBH4 in situ, afforded the tertiary amine. The effects of substituents on the aromatic ring and the steric effects of the alkyl side chain have also been studied.