30448-16-9

Basic information

• Product Name: 7-METHYLINDOLE-3-CARBOXYLIC ACID
• Synonyms: RARECHEM AL BE 1499;7-METHYLINDOLE-3-CARBOXYLIC ACID;7-METHYL-1H-INDOLE-3-CARBOXYLIC ACID;7-methylindole-3-carboxylic aicd;7-Methyl-3-indolecarboxylicacid;1H-Indole-3-carboxylic acid, 7-Methyl-;7-Methyl-3-indole acid;Indole-3-carboxylic acid, 8-methyl-
• CAS NO: 30448-16-9
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Product Categories: Indole
• Mol File: 30448-16-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 413.3 °C at 760 mmHg
• Flash Point: 203.8 °C
• Appearance: /
• Density: 1.34 g/cm³
• Vapor Pressure: 1.43E-07mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 7-METHYLINDOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHYLINDOLE-3-CARBOXYLIC ACID(30448-16-9)
• EPA Substance Registry System: 7-METHYLINDOLE-3-CARBOXYLIC ACID(30448-16-9)

Safety Data

• Hazardous Substances Data: 30448-16-9(Hazardous Substances Data)

Usage

General Description

7-Methylindole-3-carboxylic acid is a chemical compound with the molecular formula C11H9NO2. It is a derivative of indole, a heterocyclic aromatic organic compound. The chemical is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. It has potential applications in the development of anti-inflammatory agents, anti-cancer drugs, and other therapeutic compounds. 7-Methylindole-3-carboxylic acid is also used as a research chemical in the study of indole derivatives and their biological activities.

InChI:InChI=1/C10H9NO2/c1-6-3-2-4-7-8(10(12)13)5-11-9(6)7/h2-5,11H,1H3,(H,12,13)

Upstream product

• 933-67-5 7-methyl-1H-indole 
• 15719-64-9 methylammonium carbonate 
• 68-12-2 N,N-dimethyl-formamide 
• 443-47-0 2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)-ethanone 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 125818-11-3 1,7-dimethyl-1H-indole-3-carboxylic acid 
• 858515-42-1 C₃₂H₄₁N₃O₅ 

Relevant articles and documents

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NOVEL INDOL CARBOXYLIC ACID BISPYRIDYL CARBOXAMIDE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD AND COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

Disclosed herein are a new indole carboxylic acid bispyridyl carboxamide derivative, a preparation method thereof, and a composition for prevention or treatment of obesity, urinary disorders, and CNS disorders, containing the same as an active ingredient. Because the indole carboxylic acid bispyridyl carboxamide derivatives according to the present invention have high affinity for 5-HT2c receptors, act selectively on the 5-HT2c receptors, the derivatives rarely have adverse effects caused by other receptors. Because the derivatives effectively inhibit serotonin activity, they may be useful for treatment or prevention of obesity; urinary disorders such as urinary incontinence, premature ejaculation, erectile dysfunction, and prostatic hyperplasia; CNS disorders such as depression, anxiety, concern, panic disorder, epilepsy, obsessive-compulsive disorder, migraine, sleep disorder, withdrawal from drug abuse, Alzheimer's disease, and schizophrenia, associated with 5-HT2c receptors.

Novel indol carboxylic acid bispyridyl carboxamide derivatives as 5-HT2c receptor antagonists

Disclosed herein are a new indole carboxylic acid bispyridyl carboxamide derivative, a preparation method thereof, and a composition for prevention or treatment of obesity, urinary disorders, and CNS disorders, containing the same as an active ingredient. Because the indole carboxylic acid bispyridyl carboxamide derivatives according to the present invention have high affinity for 5-HT2c receptors, act selectively on the 5-HT2c receptors, the derivatives rarely have adverse effects caused by other receptors. Because the derivatives effectively inhibit serotonin activity, they may be useful for treatment or prevention of obesity; urinary disorders such as urinary incontinence, premature ejaculation, erectile dysfunction, and prostatic hyperplasia; CNS disorders such as depression, anxiety, concern, panic disorder, epilepsy, obsessive-compulsive disorder, migraine, sleep disorder, withdrawal from drug abuse, Alzheimer's disease, and schizophrenia, associated with 5-HT2c receptors.