3048-76-8

Basic information

• Product Name: 3,8-dimethyl-2,7-dioxaspiro[4.4]nonane-1,6-dione
• Synonyms: 2,7-dioxaspiro[4.4]nonane-1,6-dione, 3,8-dimethyl-
• CAS NO: 3048-76-8
• Molecular Formula: C₉H₁₂O₄
• Molecular Weight: 184.1892
• Mol File: 3048-76-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 409.9°C at 760 mmHg
• Flash Point: 220.9°C
• Density: 1.24g/cm³
• Vapor Pressure: 6.27E-07mmHg at 25°C
• Refractive Index: 1.495
• CAS DataBase Reference: 3,8-dimethyl-2,7-dioxaspiro[4.4]nonane-1,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,8-dimethyl-2,7-dioxaspiro[4.4]nonane-1,6-dione(3048-76-8)
• EPA Substance Registry System: 3,8-dimethyl-2,7-dioxaspiro[4.4]nonane-1,6-dione(3048-76-8)

Safety Data

• Hazardous Substances Data: 3048-76-8(Hazardous Substances Data)

Upstream product

• 5281-80-1 2,2'-Spirobi(5-iod-4-pentanolid) 
• 90557-34-9 diallylmalononitrile 
• 42550-76-5 cyano-diallylacetic acid methyl ester 
• 3195-24-2 diallylmalonic acid diethyl ester 
• 41890-50-0 di-tert-butyl 2,2-diallylmalonate 
• 2537-29-3 proxibarbal 
• 35357-77-8 dimethyl bisallylmalonate 
• 67-56-1 methanol 
• 4372-14-9 3,8-dimethyl-2,7-dioxa-spiro[4.4]nona-3,8-diene-1,6-dione 
• 52-43-7 5,5-diallylbarbituric acid 
• 7664-93-9 sulfuric acid 
• 75851-56-8 Sodium; 3-allyl-5-methyl-2-oxo-tetrahydro-furan-3-carboxylate 
• 4372-31-0 2,2-diallylmalonic acid 

Downstream Products

• 75-25-2 Bromoform 

Relevant articles and documents

Copper-catalysed intramolecular O-H addition to unactivated alkenes

Intramolecular cyclisation of ω-alkenoic acids and alkenols can be achieved using a catalytic amount of Cu(OTf)2 to afford lactones and cyclic ethers, offering a practical alternative to existing catalysts.

Phosphinite ligand effects in palladium(II)-catalysed cycloisomerisation of 1,6-dienes: Bicyclo[3.2.0]heptanyl diphosphinite (B[3.2.0]DPO) ligands exhibit flexible bite angles, an effect derived from conformational changes (exo- or endo-envelope) in the b

Changes in bidentate ligand structure significantly affect catalytic activity in mono-cationic Pd(II)-catalysed 1,6-diene cycloisomerisation processes to give cyclopentene products. A bicyclo-[3.2.0]heptanyl diphosphinite ligand (B[3.2.0]DPO, 3) is the fi

Synthesis of 4-Penten-4-olides (γ-Methylene-γ-butyrolactones) via 4-Pentenoic Acids

4-Penten-4-olides (γ-Methylene-γ-butyrolactones) 7 are easily accessible starting from allylic alcohols 1, which on ortho ester Claisen rearrangement and hydrolytic work-up furnish 4-pentenoic acids 5.The latter on iodolactonization and hydrogen iodide elimination by means of 1,8-diazabicycloundec-7-ene (DBU) furnish 7, in good over-all yield and with variable substitution patterns. - Iodolactonization under kinetic control shows moderate 1,2- or 1,3-asymmetric induction (3:1 and ca. 2:1, respectively).The composition of the iodolactone mixtures 6 as well as the individual relative configurations are deduced from 1H and 13C NMR data. - Similary, the spirobipentenolide 13 is obtained starting from diethyl diallylmalonate (9) via 11 resulting from ester iodocyclization.