30591-44-7

Basic information

• Product Name: cholest-5-en-3β-ol p-methylbenzoate
• Synonyms: cholest-5-en-3β-ol p-methylbenzoate
• CAS NO: 30591-44-7
• Molecular Weight: 504.797
• Mol File: 30591-44-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: cholest-5-en-3β-ol p-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: cholest-5-en-3β-ol p-methylbenzoate(30591-44-7)
• EPA Substance Registry System: cholest-5-en-3β-ol p-methylbenzoate(30591-44-7)

Safety Data

• Hazardous Substances Data: 30591-44-7(Hazardous Substances Data)

Upstream product

• 57-88-5 cholesterol 
• 874-60-2 4-methyl-benzoyl chloride 
• 110-86-1 pyridine 
• 106-43-4 para-chlorotoluene 
• 57-88-5 cholesterol 

Relevant articles and documents

Construction of Cholesterol Oxime Ether Derivatives Containing Isoxazoline/Isoxazole Fragments and Their Agricultural Bioactive Properties/Control Efficiency

To explore natural-product-based pesticidal candidates and high value-added application of cholesterol in agriculture, oximinoether derivatives of cholesterol-containing isoxazoline/isoxazole fragments (I-1～I-16 and II-1～II-18) were semiprepared by structural optimization of cholesterol. Their structures were characterized by optical rotation, high-resolution mass spectrometry (HRMS), IR, and 1H NMR spectroscopy. Particularly, the Z configurations of oxime fragments at the C-7 position of target compounds were undoubtedly determined by X-ray crystallography. Against Mythimna separata Walker, compounds 3e, I-8, I-14, and II-3 showed 2.4-2.7-fold growth inhibitory activity of the precursor cholesterol. Against Plutella xylostella Linnaeus, compounds I-6, I-7, and I-9 showed 2.4-2.7-fold oral toxicity of cholesterol. Against Aphis citricola Van der Goot, compounds 2e and II-15 exhibited 4.9 and 5.8-fold aphicidal activity of cholesterol, respectively. Notably, they showed good control effects (3.0-5.0-fold promising control efficiency of 1) against A. citricola in the greenhouse. Structure-activity relationships (SARs) suggested that the C-3 hydroxyl group and the C-7 position of cholesterol are two important modification sites. It will pave the way for future structural optimization and application of cholesterol derivatives as potential pesticidal agents in agriculture.