306935-94-4 Usage
General Description
3-(5-Formyl-2-furyl)benzenesulfonamide is a chemical compound with the molecular formula C12H9NO4S. It is an organic compound that belongs to the class of sulfa drugs, which are often used as antibiotics. This particular compound has a furan ring and a benzene ring, as well as a sulfa group. It may be used as a pharmaceutical ingredient in the development of drugs targeting bacterial and fungal infections. The formyl group in the molecule is important for its pharmaceutical activity, and the compound's structure makes it a promising candidate for further drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 306935-94-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,6,9,3 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 306935-94:
(8*3)+(7*0)+(6*6)+(5*9)+(4*3)+(3*5)+(2*9)+(1*4)=154
154 % 10 = 4
So 306935-94-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO4S/c12-17(14,15)10-3-1-2-8(6-10)11-5-4-9(7-13)16-11/h1-7H,(H2,12,14,15)
306935-94-4Relevant articles and documents
Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid
Pfefferkorn, Jeffrey A.,Greene, Meredith L.,Nugent, Richard A.,Gross, Rebecca J.,Mitchell, Mark A.,Finzel, Barry C.,Harris, Melissa S.,Wells, Peter A.,Shelly, John A.,Anstadt, Robert A.,Kilkuskie, Robert E.,Kopta, Laurice A.,Schwende, Francis J.
, p. 2481 - 2486 (2007/10/03)
A novel series of nonnucleoside HCV NS5B polymerase inhibitors were prepared from (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid, a high throughput screening lead. SAR studies combined with structure based drug design focusing on the southern heterobiaryl region of the template led to the synthesis of several potent and orally bioavailable lead compounds. X-ray crystallography studies were also performed to understand the interaction of these inhibitors with HCV NS5B polymerase.