307353-90-8 Usage
General Description
4-Chloro-6-methoxy-7-(phenylmethoxy)-3-quinolinecarboxylic acid ethyl ester is a chemical compound that belongs to the quinolinecarboxylic acid ester family. It is characterized by the presence of a chlorine atom, a methoxy group, and a phenylmethoxy group attached to a quinoline ring. 4-Chloro-6-methoxy-7-(phenylmethoxy)-3-quinolinecarboxylic acid ethyl ester is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and ability to modulate biological activities. Additionally, its ethyl ester form makes it suitable for use in various organic reactions and as a precursor for the preparation of other ester derivatives. 4-Chloro-6-methoxy-7-(phenylmethoxy)-3-quinolinecarboxylic acid ethyl ester has potential applications in the field of medicinal chemistry and drug discovery due to its structural features and pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 307353-90-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,7,3,5 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 307353-90:
(8*3)+(7*0)+(6*7)+(5*3)+(4*5)+(3*3)+(2*9)+(1*0)=128
128 % 10 = 8
So 307353-90-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H18ClNO4/c1-3-25-20(23)15-11-22-16-10-18(17(24-2)9-14(16)19(15)21)26-12-13-7-5-4-6-8-13/h4-11H,3,12H2,1-2H3
307353-90-8Relevant articles and documents
Identification of 3-amido-4-anilinoquinolines as potent and selective inhibitors of CSF-1R kinase
Scott, David A.,Balliet, Carrie L.,Cook, Donald J.,Davies, Audrey M.,Gero, Thomas W.,Omer, Charles A.,Poondru, Srinivasu,Theoclitou, Maria-Elena,Tyurin, Boris,Zinda, Michael J.
scheme or table, p. 697 - 700 (2009/08/15)
3-Amido-4-anilinoquinolines are potent and highly selective inhibitors of CSF-1R. Their synthesis and SAR is reported, along with initial efforts to optimize the physical properties and PK through modifications at the quinoline 6- and 7-positions.
