30747-21-8

Basic information

• Product Name: Adenosine, N-benzoyl-, 2',3',5'-triacetate
• CAS NO: 30747-21-8
• Molecular Formula: C23H23N5O8
• Molecular Weight: 497.464
• Mol File: 30747-21-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Adenosine, N-benzoyl-, 2',3',5'-triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-benzoyl-, 2',3',5'-triacetate(30747-21-8)
• EPA Substance Registry System: Adenosine, N-benzoyl-, 2',3',5'-triacetate(30747-21-8)

Safety Data

• Hazardous Substances Data: 30747-21-8(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 4546-55-8 N-benzoyladenosine 
• 4005-49-6 N-benzoyladenine 
• 13035-61-5 1,2,3,5-tetraacetylribose 
• 55-21-0 benzamide 
• 74465-47-7 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-bromo-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 
• 5987-73-5 2',3',5'-O-triacetyl-6-chloroinosine 

Downstream Products

• 86234-27-7 N⁶-benzoyl-8-hydroxymethyl-2',3',5'-tri-O-acetyladenosine 
• 86234-28-8 N⁶-benzoyl-2,8-di(hydroxymethyl)-2',3',5'-tri-O-acetyladenosine 
• 96695-55-5 N⁶-benzoyl-7,8-dihydro-8-hydroxymethyl-2',3',5'-tri-O-acetyladenosine 
• 86234-25-5 N⁶-benzoyl-8-methyl-2',3',5'-tri-O-acetyladenosine 
• 86234-26-6 N⁶-benzoyl-2,8-dimethyl-2',3',5'-tri-O-acetyladenosine 
• 86234-29-9 8-acetyl-N⁶-benzoyl-2',3',5'-tri-O-acetyladenosine 
• 86234-30-2 N⁶-benzoyl-2,8-diacetyl-2',3',5'-tri-O-acetyladenosine 
• 86234-31-3 N⁶-benzoyl-8-carbamoyl-2',3',5'-tri-O-acetyladenosine 
• 86234-32-4 N⁶-benzoyl-2,8-dicarbamoyl-2',3',5'-tri-O-acetyladenosine 
• 60159-28-6 N⁶-benzoyl-7,8-dihydro-2',3',5'-tri-O-acetyladenosine 

Relevant articles and documents

Selective deacylation of peracylated ribonucleosides

A protocol for chemoselective deprotection of N,O-acylated ribonucleosides has been developed. Peracylated pyrimidine ribonucleosides subjected to guanidinium nitrate and NaOMe in MeOH/CH2Cl2 at 0 °C undergo high yielding O-deacylation, while even more pronounced chemoselectivity is observed with peracylated purine ribonucleosides as O5′-acyl groups are preserved. Nucleobase-protecting groups (ABz, CBz, GiBu, and UBz) are stable to these conditions, rendering this reagent mixture as a valuable addition to the collection of protecting group protocols in nucleoside chemistry.

A direct, efficient method for the preparation of N6-protected 15N-labeled adenosines

N6-Protected adenosines have been prepared from inosines by activation of the C6 position and Pd-catalyzed coupling with amides. An efficient route to [6-15-NH2]-N6- benzoyladenosine and [1-15N,6-15NH2]-N 6-benzoyladenosine has been achieved.

The Prominent Effect of N6-Acyl Groups on the Reactivity of 9-Substituted Adenines: A New Method for the Chemical Modification of Adenines

The effect of various N6-substituents on the C(8)-hydrogen exchange of 9-substituted adenines has been estimated.The kinetic data clearly demonstrate that the N6-acyl groups significantly accelerate the C(8)-hydrogen exchange.This fa