307531-96-0 Usage
Description
2-Methyl-5-(3-(4-(Methylsulfonyl)phenyl)furan-2-yl)pyridine is an organic compound derived from the preparation process of methylsulfonylphenylbipyridine, which is a COX-2 specific inhibitor. 2-Methyl-5-(3-(4-(Methylsulfonyl)phenyl)furan-2-yl)pyridine features a pyridine ring with a methyl group at the 2nd position and a 3-(4-(methylsulfonyl)phenyl)furan-2-yl group at the 5th position, contributing to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
2-Methyl-5-(3-(4-(Methylsulfonyl)phenyl)furan-2-yl)pyridine is used as a byproduct in the synthesis of COX-2 specific inhibitors for the pharmaceutical industry. Its presence in the synthesis process suggests that it may have potential applications in the development of new drugs targeting COX-2 enzymes, which are involved in inflammation and pain.
Used in Chemical Research:
As an organic compound with a unique structure, 2-Methyl-5-(3-(4-(Methylsulfonyl)phenyl)furan-2-yl)pyridine can be used in chemical research for studying its properties, reactivity, and potential interactions with other molecules. This may lead to the discovery of new applications in various fields, including materials science, drug development, and chemical engineering.
Used in Drug Synthesis:
Given its connection to the synthesis of COX-2 specific inhibitors, 2-Methyl-5-(3-(4-(Methylsulfonyl)phenyl)furan-2-yl)pyridine may also be used as an intermediate or building block in the development of new drugs targeting COX-2 enzymes. Its unique structure could potentially be exploited to design more effective and selective inhibitors, leading to improved treatments for conditions such as arthritis, pain, and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 307531-96-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,7,5,3 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 307531-96:
(8*3)+(7*0)+(6*7)+(5*5)+(4*3)+(3*1)+(2*9)+(1*6)=130
130 % 10 = 0
So 307531-96-0 is a valid CAS Registry Number.
307531-96-0Relevant articles and documents
A practical synthesis of a COX-2-specific inhibitor
Davies,Marcoux,Corley,Journet,Cai,Palucki,Wu,Larsen,Rossen,Pye,DiMichele,Dormer,Reider
, p. 8415 - 8420 (2000)
A number of synthetic strategies to the Cox-2 specific inhibitor 1 have been described. These studies have led to the identification of a novel pyridine construction using annulation of ketone 2 using a vinamidinium species 29 and ammonia in 97% assay yield. Three approaches to the synthesis of ketone 2 are described that allow for its preparation in large quantities in >65% overall yield from methyl 6-methylnicotinate.
