307547-31-5

Basic information

• Product Name: ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate
• Synonyms: ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate
• CAS NO: 307547-31-5
• Molecular Weight: 338.36
• Mol File: 307547-31-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate(307547-31-5)
• EPA Substance Registry System: ethyl (8-methyl-4-phenyl-2H-1-benzopyran-2-on-7-yloxy)-acetate(307547-31-5)

Safety Data

• Hazardous Substances Data: 307547-31-5(Hazardous Substances Data)

Upstream product

• 93-89-0 benzoic acid ethyl ester 
• 65-85-0 benzoic acid 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 608-25-3 2-methylbenzene-1,3-diol 
• 21392-48-3 7-hydroxy-8-methyl-4-phenyl-chromen-2-one 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 1246440-45-8 C₁₈H₁₆N₂O₄ 
• 307547-34-8 2-(8-methyl-2-oxo-4-phenyl-2H-benzopyran-7-oxy)acetic acid 

Relevant articles and documents

7-substituted-4-aryl coumarins compound, and preparation method and application thereof

The invention discloses a 7-substituted-4-aryl coumarins compound, and a preparation method and an application thereof and belongs to the technical field of antitumor drugs. The 7-substituted-4-aryl coumarins compound is acquired in the manner of modifying and remolding 4 and 7 loci of the coumarins. The structural formula is shown in the specification. A pharmacological experiment proves that such a compound has an excellent antitumor activity, can be used for preparing the antitumor drugs, is capable of supplying a new selection for the development and application of the antitumor drugs and further can be applied to the design and optimization of the antitumor drugs. The preparation method of the compound has the advantages of easily acquired raw materials, mild reaction condition, easily realized synthesis method, simple reaction process and operation, low-cost reagents and higher yield.

Synthesis and docking studies of novel benzopyran-2-ones with anticancer activity

Novel series of 7-substituted-benzopyran-2-ones was synthesized by incorporating heterocyclic rings as oxadiazole, triazole, pyrazole or pyrazolin-5-one to benzopyran-2-one nucleus at p-7 via methylene-oxy or acetoxy linker. In-vitro anticancer activity w