30846-39-0

Basic information

• Product Name: POLY(L-LACTIDE GLYCOLIDE)
• Synonyms: POLY(L-LACTIDE-CO-GLYCOLIDE);POLY(L-LACTIDE GLYCOLIDE);PURASORB(R) PLG;L-LACTIDE/GLYCOLIDE COPOLYMER;i.v.0.40-0.60;(3S,6S)-3,6-Dimethyl-1,4-dioxane-2,5-dione polymer with 1,4-dioxane-2,5-dione;Glycolide-L-(-)-lactide polymer;Glycolide-lactide polymer
• CAS NO: 30846-39-0
• Molecular Formula: (C6H8O4)x.(C4H4O4)x
• Molecular Weight: 260.2
• Mol File: 30846-39-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 159-166°C
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: POLY(L-LACTIDE GLYCOLIDE)(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(L-LACTIDE GLYCOLIDE)(30846-39-0)
• EPA Substance Registry System: POLY(L-LACTIDE GLYCOLIDE)(30846-39-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 30846-39-0(Hazardous Substances Data)

Usage

Description

POLY(L-LACTIDE GLYCOLIDE), also known as Poly(L-lactide-co-glycolide) (PLGA), is a biodegradable and biocompatible copolymer synthesized from the ring-opening polymerization of lactide and glycolide. The presence of ester linkages in the polymer backbone allows for degradation via hydrolysis. The ratio of monomers and polymer block structure can be adjusted to obtain different forms of PLGA, resulting in materials with varying degrees of crystallinity, thermal transitions, solubility, and degradation rates.

Uses

Used in Medical Applications:
POLY(L-LACTIDE GLYCOLIDE) is used as a material for forming membranes in medical applications. The biodegradable and biocompatible nature of PLGA makes it suitable for various medical uses, including controlled drug delivery and wound healing.
Used in Tissue Engineering:
In the field of tissue engineering, POLY(L-LACTIDE GLYCOLIDE) is used as a scaffold. The copolymer's ability to degrade and support cell growth makes it an ideal choice for creating structures that can guide tissue regeneration and repair.
Used in Pharmaceutical Applications:
POLY(L-LACTIDE GLYCOLIDE) is used as a carrier in drug delivery systems. Its biodegradability and biocompatibility allow for controlled release of drugs, improving their efficacy and reducing side effects. Additionally, PLGA can be tailored to achieve specific drug release profiles by adjusting the monomer ratio and polymer block structure.