30893-64-2

Basic information

• Product Name: 2-(4-METHOXYPHENOXY)ACETAMIDE
• Synonyms: 2-(4-METHOXYPHENOXY)ACETAMIDE;(4-Methoxyphenoxy)acetamide
• CAS NO: 30893-64-2
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.19
• Mol File: 30893-64-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 116 °C
• Boiling Point: 384.8 °C at 760 mmHg
• Flash Point: 221.8 °C
• Appearance: /
• Density: 1.17 g/cm³
• Vapor Pressure: 3.99E-06mmHg at 25°C
• Refractive Index: 1.53
• PKA: 15.21±0.40(Predicted)
• CAS DataBase Reference: 2-(4-METHOXYPHENOXY)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENOXY)ACETAMIDE(30893-64-2)
• EPA Substance Registry System: 2-(4-METHOXYPHENOXY)ACETAMIDE(30893-64-2)

Safety Data

• Hazardous Substances Data: 30893-64-2(Hazardous Substances Data)

Usage

General Description

2-(4-methoxyphenoxy)acetamide is a chemical compound with the molecular formula C10H13NO3. It is a derivative of acetamide, with a 4-methoxyphenoxy group attached to the carbon atom. 2-(4-METHOXYPHENOXY)ACETAMIDE is commonly used in pharmaceutical and medical research, particularly in the study of analgesic and anti-inflammatory properties. It has also been investigated for its potential use as an insecticide. Due to its unique structure, it exhibits a range of biological activities and has the potential to be developed into various pharmaceutical products.

InChI:InChI=1/C9H11NO3/c1-12-7-2-4-8(5-3-7)13-6-9(10)11/h2-5H,6H2,1H3,(H2,10,11)

Upstream product

• 150-76-5 4-methoxy-phenol 
• 79-07-2 Chloroacetamide 
• 1877-75-4 2-(4-methoxyphenoxy)acetic acid 

Downstream Products

• 50800-92-5 2-(4-methoxyphenoxy)ethylamine 

Relevant articles and documents

A phenoxy acetyl amine compound preparation method and phenoxy acetamide compounds

The invention belongs to the organic intermediates and the technical field of pharmaceutical intermediates, in particular to a phenoxy acetyl amine compound preparation method and phenoxy acetyl amine compound. The present invention provides a preparation method of the pervasive should be good, and green environmental protection, has better popularization and application value. The results show that the embodiment, the invention provides the above-mentioned method can prepare a plurality of phenoxy acetyl amine compound, and the yield can be 76%.

Discovery of a new series of 5-HT1A receptor agonists

Starting from compounds previously identified as α1-adrenoceptor antagonists that were also found to bind to the 5-HT1A receptor, in an attempt to separate the two activities, a new series of 5-HT1A receptor agonists was identified and shown to have high potency and/or high selectivity. Of these, compound 13, which combines high selectivity (5-HT1A/α1 = 151) and good agonist potency (pD2 = 7.82; Emax = 76), was found to be the most interesting.