309264-67-3Relevant articles and documents
Titanium(IV)-mediated tandem deprotection-cyclodehydration of protected cysteine N-amides: Biomimetic syntheses of thiazoline- and thiazole-containing heterocycles
Raman, Prakash,Razavi, Hossein,Kelly, Jeffery W.
, p. 3289 - 3292 (2007/10/03)
(matrix presented) The scope and limitations of TiCl4-mediated Δ2-thiazoline synthesis via tandem deprotection-dehydrocyclization of trityl-protected cysteine N-amides is presented. While chemical yields are acceptable (53-96%), the