30948-01-7

Basic information

• Product Name: CHOLESTERYL 10-UNDECENOATE
• Synonyms: 3BETA-HYDROXY-5-CHOLESTENE 3[10-UNDECENOATE];3BETA-HYDROXY-5-CHOLESTENE 3-UNDECYLENATE;5-CHOLESTEN-3BETA-OL 3-[10-UNDECENOATE];CHOLESTERYL 10-UNDECENOATE;3β-hydroxy-5-cholestene 3-undecylenate;CHOLESTERYL10-UNDECANOATE;3β-Hydroxy-5-cholestene 3-undecylenate, 5-Cholesten-3β-ol 3-(10-undecenoate)
• CAS NO: 30948-01-7
• Molecular Formula: C38H64O2
• Molecular Weight: 552.91
• Mol File: 30948-01-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 79 °C
• Boiling Point: 599.3 °C at 760 mmHg
• Flash Point: 315.2 °C
• Appearance: /
• Density: 0.97 g/cm³
• Vapor Pressure: 2.54E-14mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: −20°C
• CAS DataBase Reference: CHOLESTERYL 10-UNDECENOATE(CAS DataBase Reference)
• NIST Chemistry Reference: CHOLESTERYL 10-UNDECENOATE(30948-01-7)
• EPA Substance Registry System: CHOLESTERYL 10-UNDECENOATE(30948-01-7)

Safety Data

• Hazardous Substances Data: 30948-01-7(Hazardous Substances Data)

Usage

General Description

Cholesteryl 10-undecenoate is a chemical compound that belongs to the group of cholesteryl esters. It is derived from cholesterol and undecenoic acid, and is commonly used in the production of pharmaceuticals and cosmetic products. Cholesteryl 10-undecenoate has properties that make it suitable for use as a solubilizing agent for poorly water-soluble drugs, as well as in the formulation of lipid-based drug delivery systems. It is also used in the preparation of microcrystals for drug delivery and as a stabilizer in emulsions and creams. Additionally, cholesteryl 10-undecenoate has potential applications in the treatment of various diseases, including cancer, due to its ability to improve the delivery and bioavailability of therapeutic agents.

InChI:InChI=1/C38H64O2/c1-7-8-9-10-11-12-13-14-18-36(39)40-31-23-25-37(5)30(27-31)19-20-32-34-22-21-33(29(4)17-15-16-28(2)3)38(34,6)26-24-35(32)37/h7,19,28-29,31-35H,1,8-18,20-27H2,2-6H3/t29-,31+,32+,33-,34+,35+,37+,38-/m1/s1

Upstream product

• 112-38-9 10-undecenoic acid 
• 57-88-5 cholesterol 
• 38460-95-6 undec-10-enoyl chloride 
• 57-88-5 cholesterol 

Downstream Products

• 71437-80-4 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl isonicotinate 

Relevant articles and documents

Liquid-crystalline elastomers containing sulfonic acid groups

A series of ionic liquid-crystalline (LC) elastomers were synthesized by using chemical cross-linking agents containing sulfonic acid groups, which were siloxane-based materials. A ionic divinyl monomer 2,2′-(1,2-ethenediyl)bis[5-[(4-undecenoyloxy)phenyl]azo]benzenesulfonic acid was used as chemical cross-linking agent. Cholest-5-en-3-ol(3β)-10-undecenoate was synthesized as a liquid-crystalline monomer. The effective cross-link density of the ionic elastomers was determined by swelling experiments in organic/buffer mixtures. Their liquid-crystalline properties were characterized by DSC, POM, and SAXS. A proposed multilayer buildup containing LC segment structure and ionic cross-linking lamellar structure separated by siloxane chains was given. The ion aggregated in domains forces the siloxane chains to fold and form an irregular lamellar structure. The ionic cluster lamellae may be tangled with the rigid mesogenic groups of LC segments to form multiple blocks. Liquid-crystal mesophase region of the polymers become narrow with increasing ionic cross-linking content.

Synthesis and characterization of novel fatty acid analogs of cholesterol: In vitro antimicrobial activity

In the present study we synthesized, characterized and checked the antimicrobial activity of fatty acid analogs of cholesterol. The synthesized compounds were characterized using IR, 1H NMR, 13C NMR and mass spectral data and tested for their antimicrobial activity by disk diffusion assay with slight modifications against Gram-positive, Gram-negative strains of bacteria as well as fungal strains. Minimum inhibitory concentration (MIC) of all the synthesized compounds was also determined. Compounds 7-14 showed inhibitory action against both the groups of bacteria and four strains of fungus. In vitro antimicrobial activity of the test compounds show that the compounds 10 and 13 are excellent antibacterial agents, where as compounds 13 and 14 are the excellent antifungal agents among the eight synthesized compounds.