3097-74-3

Basic information

• Product Name: 3-Methoxy-2-methyl-3-oxopropanoic acid
• Synonyms: 3-Methoxy-2-methyl-3-oxopropanoic acid;Propanedioic acid, 2-Methyl-, 1-Methyl ester;2-Methyl-malonic acid monomethyl ester
• CAS NO: 3097-74-3
• Molecular Formula: C₅H₈O₄
• Molecular Weight: 132.114
• Mol File: 3097-74-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 227.3 °C at 760 mmHg
• Flash Point: 95.7 °C
• Appearance: /
• Density: 1.205 g/cm³
• Vapor Pressure: 0.0283mmHg at 25°C
• Refractive Index: 1.433
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.87±0.34(Predicted)
• CAS DataBase Reference: 3-Methoxy-2-methyl-3-oxopropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-2-methyl-3-oxopropanoic acid(3097-74-3)
• EPA Substance Registry System: 3-Methoxy-2-methyl-3-oxopropanoic acid(3097-74-3)

Safety Data

• Hazardous Substances Data: 3097-74-3(Hazardous Substances Data)

Usage

General Description

3-Methoxy-2-methyl-3-oxopropanoic acid is a complex organic chemical compound with the molecular formula C6H10O5. It is categorized under the class of organic compounds known as beta-keto acids and derivatives, which are organic compounds containing a carbonyl group at the beta-position to at least one other carbonyl group. As a chemical, it might be used in various chemical reactions and productions; however, it's not typically found in household products or common consumer goods. The properties of this chemical, including its reactivity and potential hazards, have not been extensively studied or reported in scientific literature.

InChI:InChI=1/C5H8O4/c1-3(4(6)7)5(8)9-2/h3H,1-2H3,(H,6,7)

Upstream product

• 609-02-9 methyl-malonic acid dimethylester 
• 138434-88-5 2-Methyl-malonic acid benzyl ester methyl ester 
• 67-56-1 methanol 
• 17639-93-9 2-chloro-propionic acid methyl ester 
• 124-38-9 carbon dioxide 
• 609-08-5 Diethyl methylmalonate 
• 516-05-2 methyl-propanedioic acid 

Downstream Products

• 126356-04-5 (E)-methyl 2-methyl-3-(p-methoxyphenyl)prop-2-enoate 
• 1410941-38-6 methyl 2-methyl-3-(methyl(phenyl)amino)-3-oxopropanoate 
• 1571145-51-1 methyl 3-((2-iodophenethyl)amino)-2-methyl-3-oxopropanoate 
• 99985-60-1 methyl 2-(methyl(phenyl)amino)propanoate 
• 1265917-57-4 (E)-1-methyl 3-[2-(2-nitrovinyl)phenyl] 2-methylmalonate 
• 55063-97-3 methyl<β-(2)H2>methacrylate 

Relevant articles and documents

A one-step radical synthesis of pyrrol-2-acetic acids

Pyrrol-2-acetic acids were generated following a procedure involving I-transfer radical addition of iodoacetic acids to pyrrole with spontaneous loss of HI. This procedure also allows for efficient syntheses of 2-alkyl pyrroles through subsequent thermolytic decarboxylation.

Decarboxylative Mannich Reactions with Substituted Malonic Acid Half-Oxyesters

The decarboxylative Mannich reaction between imines and substituted malonic acids half-oxyesters (SMAHOs) has been developed using 1,4-diazabicyclo[2.2.2]octane (DABCO) as an organocatalyst. The reaction proceeds under simple reaction conditions and toler

Synthesis of α,β-Disubstituted Acrylates via Galat Reaction

Galat reactions between aldehydes and substituted malonic acids half oxyester were found to be efficiently catalyzed by morpholine in refluxing toluene. This transformation allows the stereoselective synthesis of diverse α,β-disubstituted acrylates in moderate to good yields. This method constitutes an attractive alternative to existing methods in terms of scope and eco-compatibility.