309962-63-8

Basic information

• Product Name: (S)-3-N-Boc-3-(methylamino)piperidine
• Synonyms: (S)-3-N-Boc-3-(methylamino)piperidine;(S)-TERT-BUTYLMETHYL(PIPERIDIN-3-YL)CARBAMATE;(S)-3-Boc-3-(Methylamino)piperidine;(S)-tert-butyl piperidin-3-ylMethylcarbaMate;(S)-3-(N-Boc-MethylaMino)piperidine;tert-butyl Methyl[(3S)-piperidin-3-yl]carbaMate;Methyl(3S)-3-piperidinylcarbamic acid tert-butyl ester;(S)-3-N-Boc-3-(MethylaMino)piperidine, ee: 98%
• CAS NO: 309962-63-8
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.31
• Mol File: 309962-63-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 288℃
• Flash Point: 128℃
• Appearance: /
• Density: 1.01
• Vapor Pressure: 0.00242mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.74±0.10(Predicted)
• CAS DataBase Reference: (S)-3-N-Boc-3-(methylamino)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-N-Boc-3-(methylamino)piperidine(309962-63-8)
• EPA Substance Registry System: (S)-3-N-Boc-3-(methylamino)piperidine(309962-63-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 309962-63-8(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow viscid liquid

Uses

(S)-tert-Butyl methyl(piperidin-3-yl)carbamate is a useful reactant for the synthesis substituted azoles, thiophenes and furans that act as sterol regulatory element-?binding proteins (SREBPs) inhibitors.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-6-5-7-12-8-9/h9,12H,5-8H2,1-4H3/t9-/m0/s1

Upstream product

• 309962-62-7 tert-butyl (3S)-1-(trifluoroacetyl)piperidinylcarbamate 
• 74-88-4 methyl iodide 
• 1124199-24-1 benzyl (3S)-3-[tert-butoxycarbonyl(methyl)amino]piperidine-1-carboxylate 
• 876379-22-5 benzyl (3S)-3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidine-1-carboxylate 
• 216854-23-8 tert-butyl (S)-piperidin-3-yl-carbamate 

Downstream Products

• 1374242-70-2 2-(3,5-dichlorophenylamino)-1-((S)-3-(methylamino)piperidin-1-yl)ethanone 
• 1374239-34-5 1-{(S)-3-[(2-aminopyrimidin-4-yl)methylamino]piperidin-1-yl}-2-(3,5-dichlorophenylamino)ethanone 
• 1374242-69-9 tert-butyl methyl((S)-1-(2-(3,5-dichlorophenylamino)acetyl)piperidin-3-yl)carbamate 

Relevant articles and documents

Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity

We identified (5′S)-10′-fluoro-6′-methyl-5′,6′-dihydro-3′H-spiro[cyclopropane-1,4′-[2,6]diaza[2,5]methano[2,6]benzodiazonin]-7′(1′H)-one, 22b (DS34942424) with a unique and original bicyclic skeleton. 22b showed an orally potent analgesic in the acetic ac

THERAPEUTIC ISOXAZOLE COMPOUNDS

The invention provides a compound of formula I: wherein A1, A2, A3, R1, X, Y, and B have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of monoamine oxidase B (MAO-B) enzyme function and are useful for improving cognitive function and for treating psychiatric disorders in animals.