310442-30-9

Basic information

• Product Name: 5-[[2-(Dimethylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2-methylphenol
• Synonyms: 5-[[2-(Dimethylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2-methylphenol
• CAS NO: 310442-30-9
• Molecular Weight: 283.333
• Mol File: 310442-30-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[[2-(Dimethylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[[2-(Dimethylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2-methylphenol(310442-30-9)
• EPA Substance Registry System: 5-[[2-(Dimethylamino)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2-methylphenol(310442-30-9)

Safety Data

• Hazardous Substances Data: 310442-30-9(Hazardous Substances Data)

Upstream product

• 2835-95-2 amino-4 hydroxy-2 toluene 
• 175726-62-2 4-chloro-2-dimethylaminopyrrolo<2,1-f><1,2,4>triazine 

Relevant articles and documents

Pyrrolotriazine inhibitors of kinases

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.