3112-80-9

Basic information

• Product Name: Benzene,1,1'-sulfonylbis[4-methoxy-
• Synonyms: Anisole,4,4'-sulfonyldi- (6CI,7CI,8CI); 1,1'-Sulfonylbis[4-methoxybenzene];4,4'-Dimethoxydiphenylsulfone; Bis(4-methoxyphenyl) sulfone;Bis(p-methoxyphenyl) sulfone; NSC 43075
• CAS NO: 3112-80-9
• Molecular Formula: C14H14 O4 S
• Molecular Weight: 278.329
• Mol File: 3112-80-9.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 444.7°Cat760mmHg
• Flash Point: 222.8°C
• Density: 1.232g/cm³
• CAS DataBase Reference: Benzene,1,1'-sulfonylbis[4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1,1'-sulfonylbis[4-methoxy-(3112-80-9)
• EPA Substance Registry System: Benzene,1,1'-sulfonylbis[4-methoxy-(3112-80-9)

Safety Data

• Hazardous Substances Data: 3112-80-9(Hazardous Substances Data)

Usage

General Description

Benzene,1,1'-sulfonylbis[4-methoxy- is a chemical compound with the molecular formula C14H14O6S. It is a sulfone derivative of benzene, with two methoxy (CH3O) groups attached to the benzene ring. Benzene,1,1'-sulfonylbis[4-methoxy- is used in organic synthesis and chemical reactions as a reagent and intermediate. Its properties and uses are diverse, including its application in the production of pharmaceuticals, agrochemicals, and dyes. Additionally, it serves as a building block in the synthesis of various organic compounds and materials. However, it is important to handle this chemical with care, as it can be hazardous if not used properly due to its potential to cause harm to human health and the environment.

Upstream product

• 74-83-9 methyl bromide 
• 80-09-1 4,4'-sulfonediphenol 
• 578-58-5 2-methylmethoxybenzene 
• 77-78-1 dimethyl sulfate 
• 100-66-3 methoxybenzene 
• 3393-77-9 bis(4-methoxyphenyl)sulfide 
• 1774-36-3 bis(4-methoxyphenyl) sulfoxide 
• 696-63-9 4-Methoxybenzenethiol 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 6462-50-6 sodium 4-methoxybenzenesulfinate 
• 104-94-9 4-methoxy-aniline 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 

Downstream Products

• 66294-54-0 bis-(3-chloro-4-methoxy-phenyl)-sulfone 
• 80-09-1 4,4'-sulfonediphenol 
• 46506-54-1 4-methoxy-benzene-1,3-disulfonic acid 
• 5857-42-1 4-methoxybenzenesulfonic acid 
• 3704-30-1 bis-(4-methoxy-3-nitro-phenyl)-sulfone 
• 98116-80-4 4-((4′-methoxyphenyl)sulfonyl)phenol 
• 77-46-3 acedapsone 
• 3950-59-2 bis-(3-amino-4-methoxy-phenyl)-sulfone 
• 66110-21-2 6,6'-dimethoxy-3,3'-sulfonyl-di-benzoic acid 
• 5456-51-9 4,4'-diacetoxydiphenylsulfone 
• 859331-22-9 6,6'-dimethoxy-3,3'-sulfonyl-di-benzonitrile 
• 80-08-0 dapsone 
• 368-43-4 phenylsulfonyl fluoride 
• 171364-79-7 2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Synthesis of cyanate esters based on mono-O-methylated bisphenols with sulfur-containing bridges

We described a synthetic approach to bisphenol-based monocyanate esters based on mono-O-methylation of parental bisphenols followed by cyanation of the residual phenolic hydroxyl. Structures of the synthesized compounds were determined by the application of IR, NMR 1H and 13C spectroscopies, EI and MALDI mass spectrometry, and purity of the final product was controlled by HPLC. We showed that stability of the cyanate esters depends on the nature of the bridging group. Temperature range of thermally initiated cyclotrimerization of synthesized monocyanate ester, as well as reaction enthalpy, was determined by differential scanning calorimetry (DSC).

Heterogeneous copper-catalyzed synthesis of diaryl sulfones

A carbon-supported copper nanoparticle (Cu-NP) with high catalytic activity for the synthesis of diaryl sulfones is reported. For the first time, this Cu-NP is proved to be able to effectively promote the reaction of arylboronic acids and arylsulfonyl hydrazides to generate diaryl sulfones at room temperature. The reaction shows excellent substrate universality, and substrates with different substituents can undergo the reaction smoothly, leading to the desired products in good yields. The Cu-NP is found to be made of low valence Cu based on XRD. Hence, the reaction catalyzed by the Cu-NP is believed to involve a Cu-mediated organometallic cycle.

Sulfonylation of Bismuth Reagents with Sulfinates or SO2through BiIII/BiV Intermediates

Studies to explore the catalytic activities of main-group elements are attractive. We report here our study of sulfonylation of bismuth reagents with sulfinates or SO2 surrogates. Under oxidative conditions, triarylbismuthines and sulfinates were transformed into diaryl sulfones. A transition-metal-like two-electron redox process at the Bi center was achieved in this reaction. Sulfur dioxide generated in situ can also replace sulfinates to deliver the corresponding symmetric diaryl sulfones. A rational mechanism for this reaction was also proposed that involves a Bi(III)-Bi(V) manifold.