31190-87-1 Usage
Chemical structure
Contains an aziridine ring and a hydroxyl group
Usage
Primarily used in the manufacturing of pharmaceuticals
Specific application
Building block for the synthesis of anticancer drugs (e.g., mitomycin and etoposide)
Reactivity
Reactive aziridine ring allows participation in various chemical reactions
Versatility
Acts as a versatile intermediate in organic synthesis
Hazardous nature
Classified as a hazardous chemical
Health risks
Exposure can cause irritation to skin, eyes, and respiratory tract
Potential adverse effects
Can lead to adverse health effects if not handled and used properly
Importance
Plays a crucial role in the pharmaceutical industry and other organic synthesis applications
Safety precautions
Requires careful handling and safety measures to minimize potential hazards
Check Digit Verification of cas no
The CAS Registry Mumber 31190-87-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,1,9 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 31190-87:
(7*3)+(6*1)+(5*1)+(4*9)+(3*0)+(2*8)+(1*7)=91
91 % 10 = 1
So 31190-87-1 is a valid CAS Registry Number.
31190-87-1Relevant articles and documents
N-phosphorylated amino acids as potential cytostatics
Schwieger,Unterhalt
, p. 709 - 715 (2007/10/02)
Phosphoramidic dichlorides 3 are synthesized by nucleophilic attack of methyl 2-(1-ethylenimino)-alkanoates 1 on POCl3 or by the reaction of amino acid methyl ester hydrochlorides 2 with POCl3. Subsequent treatment of 3 with ethylenimine affords the TEPA-analogs 4, and with 3-(1-ethylenimino)-1-propanol (6) the IFOSFAMID analogous 1,3,2-oxaza-phosphorines 5, the cytostatic activity of which was tested in the P388-leukemia of the CD2F1-mouse.
