3122-75-6

Basic information

• Product Name: 6-(methoxymethyl)-2-methylpyrimidin-4(1H)-one
• Synonyms: 4(1H)-pyrimidinone, 6-(methoxymethyl)-2-methyl-; 4-Pyrimidinol, 6-(methoxymethyl)-2-methyl-; 6-(Methoxymethyl)-2-methylpyrimidin-4(1H)-one; 6-(Methoxymethyl)-2-methylpyrimidin-4-ol; 6-methoxy-2-methylpyrimidin-4-ol
• CAS NO: 3122-75-6
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.1399
• Mol File: 3122-75-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 270.4°C at 760 mmHg
• Flash Point: 117.4°C
• Density: 1.222g/cm³
• Vapor Pressure: 0.00412mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 6-(methoxymethyl)-2-methylpyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(methoxymethyl)-2-methylpyrimidin-4(1H)-one(3122-75-6)
• EPA Substance Registry System: 6-(methoxymethyl)-2-methylpyrimidin-4(1H)-one(3122-75-6)

Safety Data

• Hazardous Substances Data: 3122-75-6(Hazardous Substances Data)

Upstream product

• 66762-68-3 ethyl 4-methoxy-3-oxobutanoate 
• 124-42-5 acetamidine hydrochloride 

Downstream Products

• 89966-96-1 4-methoxymethyl-2-methylpyrimidine 
• 3122-81-4 4-chloro-6-methoxymethyl-2-methylpyrimidine 

Relevant articles and documents

Studies on Pyrimidine Derivatives. XXXII. Reaction of 4-Substituted 2,6-Dimethylpyrimidine 1-Oxides with Phosphoryl Chloride

The reaction of 2,6-dimethyl-4-phenylpyrimidine 1-oxide with phosphoryl chloride gave 4-chloromethyl-2-methyl-6-phenylpyrimidine exclusively.In contrast, 2,6-dimethyl-4-methoxy-pyrimidine 1-oxide and 2,6-dimethyl-4-dimethylaminopyrimidine 1-oxide reacted with the same reagent to give the corresponding 2-chloromethylpyrimidines predominantly.Keywords - pyrimidine N-oxide; chloromethylpyrimidine; phosphoryl chloride; siteselective reaction; substituent effect