3122-78-9

Basic information

• Product Name: 4(1H)-Pyrimidinone, 6-(methoxymethyl)- (9CI)
• Synonyms: 6-(methoxymethyl)pyrimidin-4-ol;4(1H)-Pyrimidinone, 6-(methoxymethyl)- (9CI);6-(methoxymethyl)-4-pyrimidinol(SALTDATA: FREE);6-(methoxymethyl)pyrimidin-4(1H)-one
• CAS NO: 3122-78-9
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.13992
• Product Categories: PYRIMIDINE
• Mol File: 3122-78-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 155 °C
• Boiling Point: 223.238°C at 760 mmHg
• Flash Point: 88.812°C
• Appearance: /
• Density: 1.243g/cm³
• Vapor Pressure: 0.097mmHg at 25°C
• Refractive Index: 1.548
• PKA: 8.62±0.40(Predicted)
• CAS DataBase Reference: 4(1H)-Pyrimidinone, 6-(methoxymethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 6-(methoxymethyl)- (9CI)(3122-78-9)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 6-(methoxymethyl)- (9CI)(3122-78-9)

Safety Data

• Hazardous Substances Data: 3122-78-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H8N2O2/c1-10-3-5-2-6(9)8-4-7-5/h2,4H,3H2,1H3,(H,7,8,9)

Upstream product

• 66762-68-3 ethyl 4-methoxy-3-oxobutanoate 
• 41051-15-4 4-methoxyacetoacetic acid methylester 
• 463-52-5 formamidine 
• 3473-63-0 formamidine acetic acid 
• 6313-33-3 formamidine hydrochloride 

Downstream Products

• 302964-09-6 6-(methoxymethyl)pyrimidin-4-amine 
• 3122-84-7 4-chloro-6-(methoxymethyl)pyrimidine 

Relevant articles and documents

DIHYDROQUINAZOLIN-2-ONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS USEFUL IN THE TREATMENT OF HIV

The present disclosure is directed to tetrahydroquinazoline derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV na?ve cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.

Cyclic protein tyrosine kinase inhibitors

Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.