31255-47-7 Usage
Description
3-(3-Chlorophenylethyl)pyridine N-Oxide, with the CAS number 31255-47-7, is an organic compound characterized by its brown solid appearance. It is primarily recognized for its utility in the field of organic synthesis, where it serves as a valuable intermediate or building block for the creation of more complex molecules.
Uses
Used in Organic Synthesis:
3-(3-Chlorophenylethyl)pyridine N-Oxide is used as a synthetic intermediate for the development of various organic compounds. Its unique structure, which includes a chlorophenylethyl group attached to a pyridine ring with an N-oxide functional group, allows it to participate in a range of chemical reactions, facilitating the synthesis of diverse molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(3-Chlorophenylethyl)pyridine N-Oxide is used as a key component in the synthesis of novel drug candidates. Its structural features enable the design of molecules with specific biological activities, targeting various therapeutic areas such as cardiovascular, neurological, and oncological diseases. 3-(3-CHLOROPHENYLETHYL)PYRIDINE N-OXIDE's reactivity and functional group compatibility make it a versatile building block for the development of innovative pharmaceutical agents.
Used in Agrochemical Industry:
3-(3-Chlorophenylethyl)pyridine N-Oxide also finds application in the agrochemical industry, where it is utilized in the synthesis of new pesticides, herbicides, and insecticides. Its unique structural properties allow for the creation of molecules with enhanced efficacy and selectivity, contributing to the development of more effective and environmentally friendly agrochemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 31255-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,2,5 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 31255-47:
(7*3)+(6*1)+(5*2)+(4*5)+(3*5)+(2*4)+(1*7)=87
87 % 10 = 7
So 31255-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H12ClNO/c14-13-5-1-3-11(9-13)6-7-12-4-2-8-15(16)10-12/h1-5,8-10H,6-7H2
31255-47-7Relevant articles and documents
A PROCESS FOR THE MANUFACTURING OF LORATADINE AND ITS INTERMEDIATES
-
Page/Page column 14, (2010/02/15)
The process comprises (i) subjecting substituted benzyl halide to cyanation in a biphasic system using water immiscible solvents by any known methods, (ii) condensing in situ the phenyl acetonitrile thus obtained with nicotinic ester in presence of alkali metal alkoxide and water immiscible organic solvent to produce ketonitrile, (iii) hydrolyzing followed by decarboxylating the said ketonitrile in situ to respective ketone in acid environment below 60° C, (iv) subjecting the ketone so obtained to reduction followed by N-oxidation, cyanation, and hydrolysis by any known methods to produce picolinic acid, (v) cyclising the said picolinic acid to tricyclic ketone by conventional methods, (vi) treating the said tricyclic ketone with organometallic compound containing Mg to produce carbinol, (viii) purifying the said carbinol with purifying agent selected from polar water miscible organic solvent followed by dehydrating with neat sulphuric acid at the temperature below 50° C, to get N-methyl product (olefin), and subjecting the said olefin to N-carbethoxylation to produce loratadine. Loratadine can also be prepared by treating cayano compound with organometallic compound containing Mg to produce a ketone by the methods known in the art followed by cyclising in presence of a mixture of sulfuric acid and a source of boric acid to get N-methyl product and converting to loratadine by N-carbethoxylation.
