312623-85-1 Usage
Description
L-ALANINE (U-13C3; 15N) is an isotopically labeled research compound that contains three carbon-13 (13C) and one nitrogen-15 (15N) isotopes. It is a non-essential amino acid that plays a crucial role in various biological processes, including protein synthesis, glucose production, and the removal of ammonia from the body.
Uses
Used in Pharmaceutical Industry:
L-ALANINE (U-13C3; 15N) is used as a building block for the synthesis of various pharmaceutical compounds. Its isotopically labeled nature allows researchers to track and study the metabolic pathways and interactions of these compounds in the body.
Used in Metabolic Research:
L-ALANINE (U-13C3; 15N) is used as a tracer in metabolic studies to investigate the role of L-alanine in various metabolic processes, such as protein synthesis, glucose production, and ammonia detoxification. The incorporation of stable isotopes enables researchers to monitor the fate of L-alanine in biological systems and gain insights into its metabolic pathways.
Used in Kinetic Resolution:
L-ALANINE (U-13C3; 15N) is used in the synthesis of various compounds surrounding kinetic resolution. Kinetic resolution is a technique used to separate enantiomers, which are molecules that are mirror images of each other. The isotopically labeled L-alanine aids in the selective synthesis of one enantiomer over the other, providing a valuable tool for the development of chiral compounds with specific biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 312623-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,6,2 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 312623-85:
(8*3)+(7*1)+(6*2)+(5*6)+(4*2)+(3*3)+(2*8)+(1*5)=111
111 % 10 = 1
So 312623-85-1 is a valid CAS Registry Number.
312623-85-1Relevant articles and documents
Stereoselective synthesis of triply isotope-labeled Ser, Cys, and Ala: Amino acids for stereoarray isotope labeling technology
Terauchi, Tsutomu,Kobayashi, Kuniko,Okuma, Kosuke,Oba, Makoto,Nishiyama, Kozaburo,Kainosho, Masatsune
supporting information; experimental part, p. 2785 - 2787 (2009/05/30)
(Chemical Equation Presented) Efficient access to highly enantioselective isotope-labeled serine, cysteine, and alanine for stereoarray isotope labeling (SAIL) is described.
STABLE ISOTOPE-LABELED AMINO ACID, METHOD OF INTEGRATING THE SAME INTO TARGET PROTEIN, METHOD OF NMR STRUCTURAL ANALYSIS OF PROTEIN AND PROCESS FOR PRODUCING SITE-SELECTIVE STABLE ISOTOPE-LABELED FUMARIC ACID AND TARTARIC ACID
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Page 22, (2010/02/08)
The present invention provides a stable isotope-labeled amino acid which is at least one of amino acids constituting a protein and which has at least one of the following labeling patterns:(a) hydrogen atoms except at least one hydrogen atom in one or more methylene groups are deuterated,(b) hydrogen atoms in one of prochiral gem-methyl groups are completely deuterated,(c) hydrogen atoms in prochiral methyl groups are partially deuterated, and(d) all hydrogen atoms except one of them in methyl group are deuterated and hydrogen atoms in the aromatic ring are partially deuterated. With the stable isotope-labeled amino acid, the deuteration of protein can be attained without damaging the NMR sensitivity of remaining hydrogen nucleus and, in addition, the rapid, accurate analysis of NMR spectrum of a high-molecular protein which is beyond the limitation in the prior art and the determination of the stereo-structure can be performed at the same time.