312753-79-0

Basic information

• Product Name: N-benzyl-5,6-diethyl-2,3-dihydro-1H-inden-2-amine
• Synonyms: N-benzyl-5,6-diethyl-2,3-dihydro-1H-inden-2-amine
• CAS NO: 312753-79-0
• Molecular Weight: 279.425
• Mol File: 312753-79-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-5,6-diethyl-2,3-dihydro-1H-inden-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-5,6-diethyl-2,3-dihydro-1H-inden-2-amine(312753-79-0)
• EPA Substance Registry System: N-benzyl-5,6-diethyl-2,3-dihydro-1H-inden-2-amine(312753-79-0)

Safety Data

• Hazardous Substances Data: 312753-79-0(Hazardous Substances Data)

Upstream product

• 4254-29-9 indan-2-ol 
• 100-46-9 benzylamine 
• 16513-68-1 acetic acid 5-acetyl-indan-2-yl ester 
• 312753-70-1 5,6-diethyl-2,3-dihydro-1H-inden-2-amine 
• 100-52-7 benzaldehyde 
• 312753-78-9 N-(5,6-diethyl-indan-2-yl)-benzamide 

Downstream Products

• 312753-06-3 indacaterol 
• 753498-25-8 indacaterol maleate 

Relevant articles and documents

dutrow[...][...] method for the synthesis of intermediates

Disclosed is an intermediate for synthesizing indacaterol, having a structure represented by formula IV. Also disclosed are a method for synthesizing the indacaterol intermediate and a method for synthesizing indacaterol by using the intermediate. During synthesis of indacaterol, the intermediate of formula IV is reduced to obtain a chiral or racemic compound, which is then debenzylated to obtain indacaterol or a raceme thereof. By using the compound of formula IV as an intermediate for synthesizing indacaterol, the present invention provides a new route for synthesizing indacaterol, and avoids various byproducts produced in the process of synthesizing indacaterol using conventional methods.

Beta2-adrenoceptor agonists

Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.