313353-02-5

Basic information

• Product Name: 3-(morpholin-4-yl)-3-thioxopropanenitrile
• Synonyms: 3-(morpholin-4-yl)-3-thioxopropanenitrile
• CAS NO: 313353-02-5
• Molecular Weight: 170.235
• Mol File: 313353-02-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(morpholin-4-yl)-3-thioxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(morpholin-4-yl)-3-thioxopropanenitrile(313353-02-5)
• EPA Substance Registry System: 3-(morpholin-4-yl)-3-thioxopropanenitrile(313353-02-5)

Safety Data

• Hazardous Substances Data: 313353-02-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 7357-70-2 Cyanothioacetamide 

Downstream Products

• 1174304-59-6 C₁₄H₁₂Cl₂N₂O₂S 
• 1174304-38-1 3-(4-methoxyphenyl)-2-(morpholin-4-ylcarbonothioyl)acrylonitrile 
• 1258946-97-2 5-benzoyl-2-morpholinothiophene-3-carbonitrile 
• 1258946-99-4 5-(4-chlorobenzoyl)-2-morpholinothiophene-3-carbonitrile 
• 1258946-98-3 C₁₆H₁₃BrN₂O₂S 
• 1258947-00-0 5-(4-methoxybenzoyl)-2-morpholinothiophene-3-carbonitrile 
• 1202041-92-6 4-(2,4-dichlorophenyl)-5-(4,5-dihydro-1H-imidazol-2-yl)-2-morpholin-4-ylthiophene-3-carbonitrile 
• 1202041-59-5 4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)-2-morpholin-4-ylthiophene-3-carbonitrile 

Relevant articles and documents

Transamination of cyanothioacetamide with morpholine. molecular and crystal structure of 3-(morpholin-1-yl)-3-thioxopropanenitrile and 3-(morpholin-1-yl)- 3-thioxopropanethioamide

Transamination of cyanothioacetamide with equimolar amount of morpholine resulted in the formation of 3-(morpholin-1-yl)-3-thioxopropanenitrile, and with twofold excess of morpholine 3-(morpholin-1-yl)-3-thioxopropanethioamide was obtained. By the alkylation of the resulting products 2-[2-(morpholin-1-yl)-2- thioxoethylidene]thiazolidin-4-one, 3-amino-N-(4-acetylphenyl)-5-(morpholin-1- yl)-thiophene-2-carbox-amide, 3-amino-3-methylthio-1-morpholinoprop-2-ene-1- thione, (2E,4E)-2-(morpholin-4-yl)thiocarbonyl)-5-phenylpenta-2,4- dienothioamide, and 3-{2′-[2″-(molrpholin-1-yl)-2-thioxoethyl] thiazol-4′-yl}-2H-chromen-2-one were synthesized. The 3-(morpholin-1-yl)- 3-thioxopropanenitrile and 3-(morpholin-1-yl)-3-thioxopropane-thioamide structures were studied by the X-ray diffraction.