31350-99-9

Basic information

• Product Name: 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene
• Synonyms: 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene
• CAS NO: 31350-99-9
• Molecular Weight: 263.155
• Mol File: 31350-99-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene(31350-99-9)
• EPA Substance Registry System: 1-[(1-bromoethyl)sulfonyl]-4-methylbenzene(31350-99-9)

Safety Data

• Hazardous Substances Data: 31350-99-9(Hazardous Substances Data)

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 14195-15-4 α-(p-methylbenzenesulfonyl)propiophenone 
• 31378-03-7 1-phenyl-2-tosylethanone 

Downstream Products

• 1573-04-2 1-methyl-4-(octan-2-ylsulfonyl)benzene 
• 80685-00-3 (R)-1-(sec-butylsulfonyl)-4-methylbenzene 
• 80684-99-7 1-(sec-butylsulfonyl)-4-methylbenzene 
• 7569-34-8 ethyl p-tolyl sulfone 

Relevant articles and documents

Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles

Substantial advances in enantioconvergent C(sp3)-C(sp3) bond formation reactions have been made in recent years through the use of transition-metal-catalyzed cross-coupling reactions of racemic secondary alkyl electrophiles with organometallic reagents. Herein, we report a general process for the asymmetric construction of alkyl-alkyl bonds adjacent to heteroatoms, namely, a nickel-catalyzed enantioconvergent reductive hydroalkylation of olefins with α-heteroatom phosphorus or sulfur alkyl electrophiles. Including the use of readily available olefins, this reaction has considerable advantages, such as mild reaction conditions, a broad substrate scope, and good functional group compatibility, making it a desirable alternative to traditional electrophile-nucleophile cross-coupling reactions.