313657-76-0

Basic information

• Product Name: (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE
• Synonyms: 2-chloro-3-((R)-2-methylpiperazin-1-yl)pyrazine;(R)-2-Chloro-3-(2-methylpiperazin-1-yl)pyrazine;(R)-1-(3-chloro-2-pyrazinyl)-2-Methylpiperazine;2-chloro-3-[(2R)-2-methylpiperazin-1-yl]pyrazine;(2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE
• CAS NO: 313657-76-0
• Molecular Formula: C₉H₁₃ClN₄
• Molecular Weight: 212.683
• Mol File: 313657-76-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 344.609°C at 760 mmHg
• Flash Point: 162.214°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: 2-8°C
• PKA: 8.15±0.40(Predicted)
• CAS DataBase Reference: (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE(313657-76-0)
• EPA Substance Registry System: (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE(313657-76-0)

Safety Data

• Hazardous Substances Data: 313657-76-0(Hazardous Substances Data)

Usage

General Description

"(2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine" is a chemical compound that contains a piperazine ring with a chloro-pyrazinyl group attached to it. The "2R" designation refers to the stereochemistry of the molecule. (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE is used in the synthesis of pharmaceuticals and may have potential pharmacological or biochemical activities. It is important to handle this compound with caution, as it may have adverse effects if not used properly. Additionally, further research is needed to fully understand the properties and potential applications of this chemical.

InChI:InChI=1/C9H13ClN4/c1-7-6-11-4-5-14(7)9-8(10)12-2-3-13-9/h2-3,7,11H,4-6H2,1H3/t7-/m1/s1

Upstream product

• 109-07-9 (RS)-2-methylpiperazine 
• 126458-16-0 (R)-2-methylpiperazine, L-tartrate 
• 75336-86-6 (2R)-methylpiperazine 
• 313657-75-9 (3R)-3-Methyl-1-Tritylpiperazine 
• 531503-76-1 (R)-1-(3-chloro-2-pyrazinyl)-2-methyl-4-tritylpiperazine 

Downstream Products

• 639029-52-0 (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride 

Relevant articles and documents

NOVEL PROCESS

The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I). The invention also relates to (2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine, hydrochloride and a process for preparing the same. Another object of the present invention is a compound of the formula (I). Another object of the present invention is a method for the treatment or prophylaxis of a serotonin-related disorder, comprising administering to a subject in need thereof an effective amount of the compound above; as well as the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.

Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

Compounds of the general formula (I): wherein the variables are as defined in the specification are useful for the prophylaxis or treatment of serotonin-related, especially 5-HT2receptor-related, diseases in human beings or animals, particularly diseases related to the 5-HT2creceptor, especially diseases such as eating disorders, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctionions, and urinary disorders.