31377-05-6

Basic information

• Product Name: CALCIUM PIDOLATE
• Synonyms: CALCIUM PYROGLUTAMATE;CALCIUM PIDOLATE;calcium bis(5-oxo-L-prolinate);CALCIUM PCA;Pidolate calcium;Pidolic acid, calcium salt;Pyroglutamic acid calcium salt;Bis(5-oxo-L-proline)calcium salt
• CAS NO: 31377-05-6
• Molecular Formula: 2C₅H₆NO₃*Ca
• Molecular Weight: 296.29
• EINECS: 250-602-4
• Mol File: 31377-05-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 0.001g/cm3 at 20℃
• CAS DataBase Reference: CALCIUM PIDOLATE(CAS DataBase Reference)
• NIST Chemistry Reference: CALCIUM PIDOLATE(31377-05-6)
• EPA Substance Registry System: CALCIUM PIDOLATE(31377-05-6)

Safety Data

• Hazardous Substances Data: 31377-05-6(Hazardous Substances Data)

Usage

General Description

Calcium pidolate, also known as pidolic acid or L-pyroglutamic acid, is a calcium salt that is used as a nutritional supplement. It's beneficial for maintaining healthy bones, muscles, nervous system, and heart. CALCIUM PIDOLATE is soluble in water and is often administered orally to treat calcium deficiency or conditions like osteoporosis. The pidolate variant of calcium is reported to have higher bioavailability, meaning it may be better absorbed and utilized by the body compared to other forms. It's generally considered safe for consumption but should be taken as per recommended doses. Overconsumption can cause side effects like constipation and stomach issues.

InChI:InChI=1/2C5H7NO3.Ca/c2*7-4-2-1-3(6-4)5(8)9;/h2*3H,1-2H2,(H,6,7)(H,8,9);/q;;+2/p-2/t2*3-;/m00./s1

Upstream product

• 98-79-3 L-Pyroglutamic acid 

Relevant articles and documents

Metal Bonding by Amino Acids: Preparation and Crystal Structures of Calcium Bis-L-pyroglutamate and Lithium L-Pyroglutamate

Calcium bis-L-pyroglutamate and lithium L-pyroglutamate are prepared by reaction of the metal hydroxides with L-pyroglutamic acid in aqueous solution.In the solid state calcium bis-L-pyroglutamate adopts a layer structure, built up by sixteen-membered rings consisting of four L-pyroglutamate ligands bridging four calcium centers by their carboxylate groups.All three oxygen donors of the L-pyroglutamate ligands are attached to metal centers.The calcium atom lies at the center of a slightly distorted octahedron formed by four carboxylate oxygens and two amide oxygen atoms.Lithium L-pyroglutamate also features a layer structure.All three oxygen donors of the L-pyroglutamate ligand have contacts with metal atoms.The coordination sphere of the lithium atom is a slightly distorted tetrahedron consisting of three carboxylate oxygen atoms and one amide oxygen atom.The investigation of aqueous solutions of the compounds by multinuclear NMR (1H, 13C, 17O) indicates extensive electrolytic dissociation in dilute solutions.Key Words: Calcium bis-L-pyroglutamate / Lithium L-pyroglutamate / Pyroglutamate coordination and conformation