31378-00-4

Basic information

• Product Name: Benzenesulfonothioic acid, 4-methyl-, S-[(4-nitrophenyl)methyl] ester
• Synonyms: p-nitrobenzyl p-toluenethiosulfonate;4-Nitrobenzyl-p-toluolthiolsulfonat
• CAS NO: 31378-00-4
• Molecular Formula: C14H13NO4S2
• Molecular Weight: 323.394
• Mol File: 31378-00-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenesulfonothioic acid, 4-methyl-, S-[(4-nitrophenyl)methyl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonothioic acid, 4-methyl-, S-[(4-nitrophenyl)methyl] ester(31378-00-4)
• EPA Substance Registry System: Benzenesulfonothioic acid, 4-methyl-, S-[(4-nitrophenyl)methyl] ester(31378-00-4)

Safety Data

• Hazardous Substances Data: 31378-00-4(Hazardous Substances Data)

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 28519-50-8 potassium thiotosylate 
• 3753-27-3 sodium 4-methylbenzenesulfonothioate 
• 100-11-8 1-bromomethyl-4-nitro-benzene 

Downstream Products

• 102001-66-1 p-tolyl 9-fluorenyl sulfone 
• 135561-70-5 p-nitrobenzyl 9-(p-tolylsulfonyl)-9-fluorenyl trisulfide 
• 95416-92-5 C₂₁H₁₈N₂O₆S₃ 

Relevant articles and documents

Design and synthesis of garlic-related unsymmetrical thiosulfonates as potential Alzheimer's disease therapeutics: In vitro and in silico study

Garlic contains a wide range of organosulfur compounds, which exhibit a broad spectrum of biological activities. Amongst the sulfur-containing compounds in garlic, the thiosulfonates are considerably popular in various fields. In light of this, we decided

Perfluoroalkylation of Thiosulfonates: Synthesis of Perfluoroalkyl Sulfides

A practical synthesis of perfluoroalkyl sulfides is described. The method employs stable and readily accessible thiosulfonates as new electrophiles with commercial nucleophilic perfluoroalkylating reagents. The mild reaction conditions allow access to a wide variety of both aryl- and alkyl-substituted perfluoroalkyl sulfides amenable to pharmaceutical development. Furthermore, the reaction operation is straightforward, odorless, does not produce toxic wastes, and, therefore should appeal to practitioners in industrial-scale productions.