31431-19-3 Usage
Description
4-Amino-3-nitrobenzophenone is an organic compound characterized by a benzophenone core with an amino group at the 4-position and a nitro group at the 3-position. It is a yellow powder with specific chemical properties that make it a valuable intermediate in the synthesis of various heterocyclic compounds.
Uses
Used in Pharmaceutical Industry:
4-Amino-3-nitrobenzophenone is used as a key intermediate for the preparation of benzimidazoles, which are a class of compounds with significant pharmaceutical applications. Benzimidazoles are known for their wide range of biological activities, including antifungal, antibacterial, anthelmintic, and antiprotozoal properties.
Used in Chemical Synthesis:
4-Amino-3-nitrobenzophenone is also used as a versatile intermediate for the synthesis of imidazolopyridines and other imidazole-containing heterocyclic ring systems. These heterocyclic compounds are important in various fields, such as medicinal chemistry, materials science, and agrochemistry, due to their diverse applications and unique properties.
Check Digit Verification of cas no
The CAS Registry Mumber 31431-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,4,3 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 31431-19:
(7*3)+(6*1)+(5*4)+(4*3)+(3*1)+(2*1)+(1*9)=73
73 % 10 = 3
So 31431-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H10N2O3/c14-11-7-6-10(8-12(11)15(17)18)13(16)9-4-2-1-3-5-9/h1-8H,14H2
31431-19-3Relevant articles and documents
Preparation method of 3-acetylindole BRPF1 inhibitor and use of 3-acetylindole BRPF1 inhibitor
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, (2020/03/03)
The invention relates to a 3-acetylindole compound of a novel structure shown in a formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate or a solvate thereof, a preparation method of the compound, a pharmaceutical composition containing a therapeutically effective dose of the compound, and use thereof as a protein tyrosine kinase inhibitor, especially as a bromine-containing area PHD zinc finger protein 1 (BRPF1) inhibitor, in the prevention or treatment of disease benefited from the inhibition of BRPF1.
Zinc Mediated Friedel-Crafts Acylation in Solvent-Free Conditions under Microwave Irradiation
Paul, Satya,Nanda, Puja,Gupta, Rajive,Loupy, Andre
, p. 2877 - 2881 (2007/10/03)
Zn powder is found to catalyze the Friedel-Crafts acylation of aromatic compounds with acyl halides efficiently under microwave irradiation in solvent-free conditions. Activated substrates undergo acylation predominantly at the para-position. The Zn powder can be re-used up to six times after simple washing with diethyl ether and dilute HCl.
AN ALTERNATE SYNTHESIS OF 3,4-DIAMINOBENZOPHENONE AND OF MEBENDAZOLE
Ayyangar, N. R.,Lahoti, R. J.,Daniel, Thomas
, p. 627 - 632 (2007/10/03)
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