315204-36-5

Basic information

• Product Name: Benzaldehyde, 2,4-difluoro-5-methyl- (9CI)
• Synonyms: Benzaldehyde, 2,4-difluoro-5-methyl- (9CI);2,4-Difluoro-5-methylbenzaldehyde
• CAS NO: 315204-36-5
• Molecular Formula: C₈H₆F₂O
• Molecular Weight: 156.1294464
• Product Categories: HALIDE;ALDEHYDE
• Mol File: 315204-36-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 199.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Benzaldehyde, 2,4-difluoro-5-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,4-difluoro-5-methyl- (9CI)(315204-36-5)
• EPA Substance Registry System: Benzaldehyde, 2,4-difluoro-5-methyl- (9CI)(315204-36-5)

Safety Data

• Hazardous Substances Data: 315204-36-5(Hazardous Substances Data)

Usage

General Description

Benzaldehyde, 2,4-difluoro-5-methyl- (9CI) is a chemical compound with the molecular formula C8H6F2O. It is a colorless liquid with a sweet, aromatic scent and is commonly used as a flavoring agent in the food and beverage industry. Benzaldehyde, 2,4-difluoro-5-methyl- (9CI) is also utilized in the production of fragrances, dyes, and pharmaceuticals. Its chemical structure contains two fluorine atoms and a methyl group, which give it unique properties that make it useful in various industrial applications. Additionally, benzaldehyde, 2,4-difluoro-5-methyl- (9CI) has potential as a building block in organic synthesis due to its reactivity and ability to undergo various chemical reactions.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 159277-47-1 1-bromo-2,4-difluoro-5-methylbenzene 
• 119072-55-8 tert-butylisonitrile 
• 2591-86-8 N-Formylpiperidine 

Downstream Products

• 1354960-68-1 4-[4-chloro-3-(trifluoromethyl)phenoxy]-2-fluoro-5-methylbenzaldehyde 
• 315204-47-8 5-(2,4-difluoro-5-methyl-benzyloxy)-2-phenyl-[1,3]dioxane 
• 315204-37-6 1-(bromomethyl)-2,4-difluoro-5-methylbenzene 
• 329314-57-0 2,4-difluoro-5-methylphenethylamine 
• 315204-46-7 (2,4-difluoro-5-methyl-phenyl)-methanol 
• 417706-33-3 1-(2,4-difluoro-5-methylphenyl)-2-nitroethanol 

Relevant articles and documents

Design and synthesis of N-nonpolar nucleobase dipeptides: Application of the Ugi reaction for the preparation of dipeptides havingfluoroarylalkyl groups appended to the nitrogen atom

A single-step one-pot synthesis based on the Ugi four-component condensation of previously unknown dipeptides, 2,3,4 and 5, having afluoroaromatic group appended to the nitrogen atom, is described. The series of dipeptides produced here can be viewed as nonpolar nucleobase dipeptides since the difluorotoluene nucleoside 1 is a well known nonpolar analogue of natural thymidine. A mixture of N-protected amino acids 7, fluorophenethylamines 6, isocyanides 8, and acetone or paraformaldehyde are stirred in methanol in the presence of 3 A molecular sieves to furnish the N-fluoroarylethyl-Aib- or -Gly-containing dipeptides 2 or 3, in moderate yields. The dipeptides 2d and 3b, having a cyclohex-1-enamide moiety, are deprotected readily with 3 M HCl in THF to a3ord the free dipeptides in high yields. The N-fluoroarylmethyl-Aib- or -Gly-containingβ-alanyl dipeptides 4 or 5, designed based on the structure of 2′,5′-linked isoDNA, are also synthesized in a similar fashion to the preparation of 2, in moderate to good yields as both protected and free dipeptides.

Syntheses of 1-[(2-hydroxyethoxy)methyl]- and 1-[(1,3-Dihydroxy-2-propoxy)methyl]- derivatives of 5-substituted-2,4-Difluorobenzene: Unnatural acyclo thymidine mimics for evaluation as anticancer and antiviral agents

A group of 1-[(2-hydroxyethoxy)methyl]- (12) and 1-[(1,3-dihydrdxy-2-propoxy)methyl]- (13) derivatives of 2,4-difluorobenzene possessing a variety of C-5 substituents (R = Me, H, I, NO2) were designed with the expectation that they may serve as