315228-23-0

Basic information

• Product Name: Quinoline, 3-(2,6-dichloro-4-nitrophenoxy)-
• CAS NO: 315228-23-0
• Molecular Formula: C15H8Cl2N2O3
• Molecular Weight: 335.146
• Mol File: 315228-23-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Quinoline, 3-(2,6-dichloro-4-nitrophenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 3-(2,6-dichloro-4-nitrophenoxy)-(315228-23-0)
• EPA Substance Registry System: Quinoline, 3-(2,6-dichloro-4-nitrophenoxy)-(315228-23-0)

Safety Data

• Hazardous Substances Data: 315228-23-0(Hazardous Substances Data)

Upstream product

• 580-18-7 3-hydroxyquinoline 
• 20098-48-0 3,4,5-trichloronitrobenzen 

Downstream Products

• 315224-26-1 2,4-dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide 
• 315224-25-0 C₂₂H₁₂Cl₃F₃N₂O₃S 
• 315228-24-1 3,5-dichloro-4-(quinolin-3-yloxy)aniline 

Relevant articles and documents

Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor central to fatty acid and glucose homeostasis. PPARγ is the molecular target for type 2 diabetes mellitus (T2DM) therapeutics TZDs (thiazolidinediones), full agonists of PPARγ with

SALTS AND POLYMORPHS OF A POTENT ANTIDIABETIC COMPOUND

Salts and polymorphs of a compound useful in the treatment of inflammatory and metabolic conditions and diseases are provided herein. In particular, the invention provides salts and polymorphs of a compound which modulates the expression and/or function of a peroxisome proliferator-activated receptor. The salts and polymorphs are useful for the treatment or prevention of conditions and disorders associated with energy homeostasis such as type II diabetes, lipid metabolism, adipocyte differentiation and inflammation.