3153-34-2 Usage
Description
ISO-PROPYLCHLOROBUTYRATE, also known as Isopropyl 4-Chlorobutyrate, is an organic compound that is primarily recognized as an impurity in the pharmaceutical compound Vilazodone (V265000). Vilazodone is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist, which is under clinical evaluation for the treatment of major depression. ISO-PROPYLCHLOROBUTYRATE is characterized by its chemical structure and properties, which contribute to its presence in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
ISO-PROPYLCHLOROBUTYRATE is used as an impurity in the development and production of Vilazodone (V265000) for the treatment of major depression. Its presence in the pharmaceutical compound is significant as it may affect the overall efficacy and safety profile of the drug under clinical evaluation.
As an impurity in Vilazodone:
ISO-PROPYLCHLOROBUTYRATE is used as a component in the synthesis of Vilazodone, where it plays a role in the development of the combined SSRI and 5-HT1A receptor partial agonist. The presence of this impurity is crucial for the pharmaceutical industry to understand its potential impact on the drug's effectiveness and safety in treating major depression.
Check Digit Verification of cas no
The CAS Registry Mumber 3153-34-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,5 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3153-34:
(6*3)+(5*1)+(4*5)+(3*3)+(2*3)+(1*4)=62
62 % 10 = 2
So 3153-34-2 is a valid CAS Registry Number.
3153-34-2Relevant articles and documents
Insight into the mechanism and stereochemistry of the transformations of alkyltitanium Ate-Complexes. An enhanced enantioselectivity in the cyclopropanation of the carboxylic esters with titanacyclopropane reagents
Kulinkovich, Oleg G.,Kananovich, Dzmitry G.,Lopp, Margus,Snieckus, Victor
supporting information, p. 3615 - 3626 (2015/01/16)
The dependence of the stereoselectivity of the cyclopropanation reaction of g,g-diphenyl-g-butyrolactone and carboxylic esters with alkylmagnesium bromides in the presence of titanium(IV) TADDOLates on the structure of the reactants has been examined in d
