316-00-7

Basic information

• Product Name: 1,1'-Biphenyl, 4,4'-difluoro-2,2'-dinitro-
• CAS NO: 316-00-7
• Molecular Formula: C12H6F2N2O4
• Molecular Weight: 280.187
• Mol File: 316-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl, 4,4'-difluoro-2,2'-dinitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl, 4,4'-difluoro-2,2'-dinitro-(316-00-7)
• EPA Substance Registry System: 1,1'-Biphenyl, 4,4'-difluoro-2,2'-dinitro-(316-00-7)

Safety Data

• Hazardous Substances Data: 316-00-7(Hazardous Substances Data)

Usage

Type of Compound

Biphenyl derivative

Structural Features

Contains two fluorine atoms and two nitro groups

Electronegativity

Highly electronegative

Reactivity

Highly reactive

Explosiveness

Potentially explosive

Applications

Used in the manufacturing of advanced materials and explosives

Health Hazards

Toxic, can cause severe chemical burns and respiratory issues upon contact

Environmental Impact

Poses a significant hazard to the environment

Safety Precautions

Requires strict safety protocols and regulations for handling and transport

Upstream product

• 80517-21-1 4-fluoro-2-nitrobenzonitrile 

Relevant articles and documents

FLUORINATED TRICYCLIC NEUROLEPTICS WITH PROLONGED ACTION: 7-FLUORO-11--2-ISOPROPYL-10,11-DIHYDRODIBENZOTHIEPIN

Substitution reaction of 11-chloro-7-fluoro-2-isopropyl-10,11-dihydrodibenzothiepin with 1-(2-hydroxyethyl)piperazine gave the title compound I which proved a very potent and long acting oral neuroleptic agent ("isofloxythepin").Its resolution by means of dibenzoyl-(+)- and (-)-tartaric acid led to (-)- and (+)-enantiomer out of which the former represents the neuroleptically active component.In the synthetic sequence leading to I, preparation of two key intermediates was re-elaborated using new partial sequences: 4-fluoro-2-iodobenzoic acid (XIII) from 4-fluoro-2-nitroaniline (V) via the nitrile VI and the acids VIII and XII, and acetic acid (XVIII) from XIII via XIV and the compounds XV-XVII.The sulfoxides and N-oxides XIX-XXII were prepared as potential metabolites of isofloxithepin (I).