317334-99-9

Basic information

• Product Name: 1,1'-((5-bromo-1,3-phenylene)bis(methylene))bis(1H-pyrazole)
• Synonyms: 1,1'-((5-bromo-1,3-phenylene)bis(methylene))bis(1H-pyrazole)
• CAS NO: 317334-99-9
• Molecular Weight: 317.188
• Mol File: 317334-99-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,1'-((5-bromo-1,3-phenylene)bis(methylene))bis(1H-pyrazole)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-((5-bromo-1,3-phenylene)bis(methylene))bis(1H-pyrazole)(317334-99-9)
• EPA Substance Registry System: 1,1'-((5-bromo-1,3-phenylene)bis(methylene))bis(1H-pyrazole)(317334-99-9)

Safety Data

• Hazardous Substances Data: 317334-99-9(Hazardous Substances Data)

Upstream product

• 556-96-7 5-bromo-1,3-xylene 
• 288-13-1 NH-pyrazole 
• 51760-23-7 1-bromo-3,5-bis(bromomethyl)benzene 

Downstream Products

• 317335-02-7 3,5-bis-pyrazol-1-ylmethylbenzoic acid 
• 317335-03-8 3,5-bis-pyrazol-1-ylmethylbenzoyl chloride 
• 317333-78-1 1-[3,5-bis(1H-pyrazol-1-ylmethyl)phenyl]-3-(1H-imidazol-2-yl)propane-1,3-dione 
• 317333-76-9 1-(3,5-bis-pyrazol-1-ylmethylphenyl)-3-pyrimidin-2-yl-propane-1,3-dione 
• 317335-01-6 ethyl 3,5-bis-pyrazol-1-ylmethylbenzoate 

Relevant articles and documents

CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.