31792-47-9

Basic information

• Product Name: 2-THIOPHEN-2-YL-QUINOLINE-4-CARBOXYLIC ACID
• Synonyms: IFLAB-BB F0239-1084;AKOS B000575;AKOS BBS-00000715;AKOS BB-9096;2-THIOPHEN-2-YL-QUINOLINE-4-CARBOXYLIC ACID;2-THIEN-2-YLQUINOLINE-4-CARBOXYLIC ACID;2-(2-THIENYL)-4-QUINOLINECARBOXYLIC ACID;TIMTEC-BB SBB007348
• CAS NO: 31792-47-9
• Molecular Formula: C₁₄H₉NO₂S
• Molecular Weight: 255.29
• Mol File: 31792-47-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 211 °C(Solv: ethanol (64-17-5))
• Boiling Point: 458.1 °C at 760 mmHg
• Flash Point: 230.8 °C
• Appearance: /
• Density: 1.386 g/cm³
• Vapor Pressure: 3.47E-09mmHg at 25°C
• Refractive Index: 1.712
• PKA: 0.93±0.10(Predicted)
• CAS DataBase Reference: 2-THIOPHEN-2-YL-QUINOLINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-THIOPHEN-2-YL-QUINOLINE-4-CARBOXYLIC ACID(31792-47-9)
• EPA Substance Registry System: 2-THIOPHEN-2-YL-QUINOLINE-4-CARBOXYLIC ACID(31792-47-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 31792-47-9(Hazardous Substances Data)

Usage

General Description

2-Thiophen-2-yl-quinoline-4-carboxylic acid is a chemical compound that consists of a quinoline ring fused with a thiophene ring and a carboxylic acid group. It is a heterocyclic compound with potential biological and pharmacological activities. The presence of the thiophene and quinoline moieties in the structure of this compound could endow it with various biological properties, making it potentially useful in medicinal chemistry for the development of new drugs. Additionally, the carboxylic acid group allows for the compound to be easily modified and used as a building block for the synthesis of other organic molecules. Overall, 2-Thiophen-2-yl-quinoline-4-carboxylic acid is a versatile chemical compound with potential applications in pharmaceutical research and drug development.

InChI:InChI=1/C14H9NO2S/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)

Upstream product

• 88-15-3 2-Acetylthiophene 
• 91-56-5 indole-2,3-dione 
• 78660-85-2 3-hydroxy-3-(2-oxo-2-(thiophen-2-yl)ethyl)indolin-2-one 
• 6165-68-0 thiophene boronic acid 
• 5467-57-2 2-chloroquinoline-4-carboxylic acid 

Downstream Products

• 326870-59-1 N-[2-chloro-5-(trifluoromethyl)phenyl]-2-(thiophen-2-yl)quinoline-4-carboxamide 
• 40619-52-1 2-(5-nitro-thiophen-2-yl)-quinoline-4-carboxylic acid anilide 
• 39072-27-0 2-thiophen-2-yl-quinoline-4-carboxylic acid {4-[bis-(2-chloro-ethyl)-amino]-benzylidene}-hydrazide 
• 39078-36-9 2-thiophen-2-yl-quinoline-4-carboxylic acid (3-nitro-benzylidene)-hydrazide 
• 39072-18-9 2-thiophen-2-yl-quinoline-4-carboxylic acid (4-nitro-benzylidene)-hydrazide 
• 39078-35-8 2-thiophen-2-yl-quinoline-4-carboxylic acid (2-nitro-benzylidene)-hydrazide 
• 39072-26-9 2-thiophen-2-yl-quinoline-4-carboxylic acid (4-dimethylamino-benzylidene)-hydrazide 
• 39072-25-8 2-thiophen-2-yl-quinoline-4-carboxylic acid (4-methoxy-benzylidene)-hydrazide 
• 39078-34-7 2-thiophen-2-yl-quinoline-4-carboxylic acid benzylidenehydrazide 
• 39072-28-1 2-(thiophen-2-yl)quinoline-4-carbohydrazide 
• 40619-51-0 5-(4-N-Phenylcarboxamido-2-chinolyl)thiophen 
• 34243-33-9 2-thiophen-2-yl-quinoline 

Relevant articles and documents

Synthesis and pharmacological properties of some quinoline derivatives

A series of 2-(2-thienyl)cinchoninic acids 3, their derivatives 5 and 4-(3-substituted-1,2,4-triazolo[3,4-b]- 1,3,4-thiaziazolo-6-yl)-2-(2-thienyl)quinolines 6 were synthesized. The structures of the newly synthesized compounds are confirmed by analytical, IR, NMR and mass spectral data. The newly synthesized compounds were evaluated for their anti-inflammatory, analgesic and anthelmintic activity. The results indicated that dinitrothiophene derivatives 5 are more active.

Quinoline-4-carboxamide skeleton derivative and application thereof

The invention discloses a quinoline-4-formamide skeleton derivative and application thereof, belonging to the field of chemical medicines. The invention provides a compound as shown in a formula I or pharmaceutically acceptable salt thereof. The invention

Discovery of Potent Small-Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-Pancreatic Ductal Adenocarcinoma Activity

SIRT6 activation is thought to be a promising target for the treatment of many diseases, particularly cancer. Herein, we report the discovery of a series of new small-molecule SIRT6 activators. Structure-activity relationship analyses led to the identific