31843-80-8

Basic information

• Product Name: Adenosine, N-benzoyl-3'-deoxy-3'-[(diethoxyphosphinyl)methyl]-, 2'-acetate 5'-benzoate
• CAS NO: 31843-80-8
• Molecular Formula: C31H34N5O9P
• Molecular Weight: 651.613
• Mol File: 31843-80-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Adenosine, N-benzoyl-3'-deoxy-3'-[(diethoxyphosphinyl)methyl]-, 2'-acetate 5'-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-benzoyl-3'-deoxy-3'-[(diethoxyphosphinyl)methyl]-, 2'-acetate 5'-benzoate(31843-80-8)
• EPA Substance Registry System: Adenosine, N-benzoyl-3'-deoxy-3'-[(diethoxyphosphinyl)methyl]-, 2'-acetate 5'-benzoate(31843-80-8)

Safety Data

• Hazardous Substances Data: 31843-80-8(Hazardous Substances Data)

Upstream product

• 91684-84-3 Benzoic acid (2S,3R,4R)-4-acetoxy-5-chloro-3-(diethoxy-phosphorylmethyl)-tetrahydro-furan-2-ylmethyl ester 
• 17187-65-4 6-benzamido-9-(chloromercuri)purine 
• 31843-73-9 ((3aR,5S,6R)-5-Formyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-ylmethyl)-phosphonic acid diethyl ester 
• 91684-83-2 (E)-3-deoxy-3-diethoxyphosphinylmethylene-1,2;5,6-di-O-isopropylidene-α-D-ribo-hexofuranose 
• 1660-94-2 Tetraethyl methylenediphosphonate 
• 31843-75-1 5-O-benzoyl-3-deoxy-3-diethoxyphosphorylmethyl-1,2-O-isopropylidene-α-D-ribofuranose 
• 31843-71-7 3-deoxy-3-[(diethoxyphosphoryl)methyl]-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 31843-74-0 3-deoxy-3-diethoxyphosphinylmethyl-1,2-O-isopropylidene-α-D-ribofuranose 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 31843-77-3 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-O-(diethoxyphosphonomethyl)-β-D-ribofuranose 
• 4005-49-6 N-benzoyladenine 

Downstream Products

• 90012-84-3 9-(5-O-benzoyl-3-deoxy-3-diethoxyphosphorylmethyl-β-D-ribofuranosyl)adenine 
• 133272-00-1 C₂₀H₂₃N₅O₇P^(1-)*Na⁽¹⁺⁾ 
• 90012-85-4 9-(5-O-benzoyl-3-deoxy-3-diethoxyphosphorylmethyl-2-O-phenoxythiocarbonyl-β-D-ribofuranosyl)adenine 
• 90012-86-5 9-(5-O-benzoyl-2,3-dideoxy-3-diethoxyphosphorylmethyl-β-D-ribofuranosyl)adenine 

Relevant articles and documents

Synthesis of 2',3'-Dideoxy-3'-(phosphonomethyl)nucleosides, Phosphonate Analogs of 2'-Deoxy-3'-nucleotides

1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-(diethoxyphosphorylmethyl)-β-D-ribofuranose (8) is linked (a) to the protected purine bases ABz, GiB and T, respectively, in the presence of potassium nonaflate and (b) to the silylated pyrimidin

2',3'-Dideoxy-3'-C-(phosphonomethyl)adenosine, the Phosphonate Analogue of 2'-Deoxyadenosine 3'-Phosphate

The title compound 7 is prepared in a five-step synthesis starting from 1,2-di-O-acetyl-5-O-benzoyl-3-deoxy-3-O-(diethoxyphosphonomethyl)-β-D-ribofuranose (2).The preferred conformation of 7 is derived from its 1H and 13C NMR data. - Keywords: Nucleotide