31848-01-8 Usage
Originator
Plausitin,Carlo Erba,Italy,1975
Manufacturing Process
Sodium methoxide (1.2 g) in dimethylformamide (150 ml) was stirred with
3,5-dimethoxy-4'-chloro-4-hydroxybenzophenone (6 g) in dimethylformamide
(50 ml), for 2 hours at 120°C. The reaction mixture was then treated with β-
morpholinoethyl chloride (3.4 g) and heated for 1 hour at 140C, then
evaporated to dryness, and treated with water to give a solid material. The
mixture was filtered, washed and crystallized from cyclohexane to give 3,5-
dimethoxy-4'-chloro-4-(β-morpholinoethoxy)-benzophenone (6.5 g), MP 91°C
to 92°C. The product was then reacted at about 0°C with gaseous hydrogen
chloride in ether to give, after crystallization from isopropanol, the
corresponding hydrochloride which had a MP of 187.9°C.
Therapeutic Function
Antitussive
Check Digit Verification of cas no
The CAS Registry Mumber 31848-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,4 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 31848-01:
(7*3)+(6*1)+(5*8)+(4*4)+(3*8)+(2*0)+(1*1)=108
108 % 10 = 8
So 31848-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H24ClNO5/c1-25-18-13-16(20(24)15-3-5-17(22)6-4-15)14-19(26-2)21(18)28-12-9-23-7-10-27-11-8-23/h3-6,13-14H,7-12H2,1-2H3
