31892-41-8 Usage
Description
1H-Benzimidazole-1-carbonitrile(9CI), also known as 1-Cyanobenzimidazole, is an organic compound with the molecular formula C8H6N2. It is a derivative of benzimidazole, featuring a nitrile functional group (C≡N) attached to the imidazole ring. 1H-Benzimidazole-1-carbonitrile(9CI) is known for its versatile chemical properties and potential applications in various industries.
Uses
1. Used in Chemical Synthesis:
1H-Benzimidazole-1-carbonitrile(9CI) is used as a key intermediate in the synthesis of various organic compounds, such as alkyl benzimidazole-1-carboximidates and 1H-benzimidazole-1-carbohydrazonamide. It is used as a starting material for these compounds by reacting with aliphatic alcohols and an excess of hydrazine, respectively.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1H-Benzimidazole-1-carbonitrile(9CI) serves as an important building block for the development of new drugs. Its unique chemical structure allows for the creation of a wide range of bioactive molecules with potential therapeutic applications.
3. Used in Electrophilic Cyanation Reactions:
1H-Benzimidazole-1-carbonitrile(9CI) is used as an electrophilic cyanating reagent in cyanation reactions, including those involving aryl and heteroaryl Grignard reagents. This application is crucial for the synthesis of various organic compounds with cyano groups, which are essential in the development of new materials and pharmaceuticals.
4. Used in Material Science:
In the field of material science, 1H-Benzimidazole-1-carbonitrile(9CI) can be utilized in the development of novel materials with specific properties, such as conductivity, magnetism, or optical characteristics. Its unique structure and reactivity make it a valuable component in the design and synthesis of advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 31892-41-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,9 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 31892-41:
(7*3)+(6*1)+(5*8)+(4*9)+(3*2)+(2*4)+(1*1)=118
118 % 10 = 8
So 31892-41-8 is a valid CAS Registry Number.
31892-41-8Relevant articles and documents
Synthesis of 1-cyanobenzimidazole derivatives and their effect on rat erythrocyte resistance
Purygin,Sergeeva,Kuz'mina,Labazova
, p. 415 - 417 (2002)
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2-quinoxalinylnitrenes and 4-quinazolinylnitrenes: Rearrangement to cyclic and acyclic carbodiimides and ring-opening to nitrile ylides
Kvaskoff, David,Vosswinkel, Michael,Wentrup, Curt
supporting information; experimental part, p. 5413 - 5424 (2011/06/21)
This work was undertaken with the aim to obtain direct evidence for the interrelationships between hetarylnitrenes, their ring-expanded cyclic carbodiimide isomers, and ring-opened nitrile ylides. Tetrazolo[1,5-a] quinoxaline 11T and tetrazolo[5.1-c]quina
Quantitative gas-solid reactions with ClCN and BrCN: Synthesis of cyanamides, cyanates, thiocyanates, and their derivatives
Kaupp, Gerd,Schmeyers, Jens,Boy, Juergen
, p. 2467 - 2474 (2007/10/03)
Gas-solid reaction techniques allow quantitative cyanations with ClCN and BrCN. Three primary and four secondary cyanamides, a cyanimide, four cyanates, and four thiocyanates were all prepared as solids in 100% yield from solid anilines, benzimidazoles, imides, phenolates, and thiolates, respectively. Intramolecular solid-state reactions of cyanated o-aminophenol and of cyanated hydrazides gave heterocyclic compounds. When comparable reactions were performed in solution the reported product yields were considerably less than 100% in all cases. The reasons for the success of the environmentally benign solid-state syntheses are discussed in terms of phase rebuilding, phase transformation, and crystal disintegration. Atomic force microscopy (AFM) of selected systems indicates the occurrence of long-range molecular movements which are governed by the crystal packing. This is evident from the obvious correlations between the molecular movements and the known crystal packing data. A new type of geometric surface feature, a rectangular and a rhombic depression which resembles a swimming-pool basin, was found in the cyanation of o-aminophenol and benzohydrazide.