319458-58-7

Basic information

• Product Name: 4(1H)-Pyrimidinone, 2,6-diamino-5-[1-(nitromethyl)-3-(phenylmethoxy)propyl]-
• CAS NO: 319458-58-7
• Molecular Formula: C15H19N5O4
• Molecular Weight: 333.347
• Mol File: 319458-58-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Pyrimidinone, 2,6-diamino-5-[1-(nitromethyl)-3-(phenylmethoxy)propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Pyrimidinone, 2,6-diamino-5-[1-(nitromethyl)-3-(phenylmethoxy)propyl]-(319458-58-7)
• EPA Substance Registry System: 4(1H)-Pyrimidinone, 2,6-diamino-5-[1-(nitromethyl)-3-(phenylmethoxy)propyl]-(319458-58-7)

Safety Data

• Hazardous Substances Data: 319458-58-7(Hazardous Substances Data)

Upstream product

• 100643-27-4 2,6-diamino-3H-pyrimidin-4-one 
• 319458-57-6 (E)-(((4-nitrobut-3-en-1-yl)oxy)methyl)benzene 
• 19790-60-4 3-Benzyloxypropanal 
• 319458-56-5 4-benzyloxy-1-nitro-butan-2-ol 

Downstream Products

• 319458-59-8 4-(benzyloxy)-2-(2,4-diamino-6-oxo-1,6-dihydro-5-pyrimidinyl)butanal oxime 
• 319458-60-1 2-amino-5-[2-(benzyloxy)ethyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one 

Relevant articles and documents

A new and versatile synthesis of 5-substituted pyrrolo[2,3-d]pyrimidines

We have developed a new methodology for the construction of 5-substituted pyrrolo[2,3-d]pyrimidines that involves the reduction of a nitroalkane to an oxime using the reducing ability of the Sn(SR3)- species, followed by mild, acid-catalysed deoximation of the resulting adduct using Dowex-H+ resin to form an intermediate aldehyde that spontaneously cyclises to the fused pyrrole ring. (C) 2000 Elsevier Science Ltd.