3198-29-6 Usage
Description
1,2-Benzenedicarboxylicacid, ion(2-), also known as phthalate esters, are a group of plasticizers that include di-(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DINP) as the most widely used phthalates. They are mainly used as constituents of many commercial products such as cosmetics, paper coating, paints, and adhesives. Phthalates have been of great concern due to their potential side effects on children's health and their presence as environmental pollutants.
Uses
Used in Personal Care Products and Cosmetics:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a plasticizer in personal care products and cosmetics to increase the flexibility and durability of these products.
Used in Plastics:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a plasticizer in the production of soft vinyl plastics, making them more pliable and easier to work with.
Used in Paper Coating:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a plasticizer in paper coating to improve the flexibility and durability of the paper.
Used in Paints and Adhesives:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a plasticizer in paints and adhesives to improve their flexibility, adhesion, and durability.
Used in Medical Devices:
1,2-Benzenedicarboxylicacid, ion(2-) is used in the production of certain medical devices, such as cardiac catheters and endotracheal tubes, to improve their flexibility and durability.
Used in Wires, Cables, Hoses, and Plastic Toys:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a plasticizer in the production of wires, cables, hoses, and plastic toys to improve their flexibility and durability.
Used in Enteric-Coated Pharmaceutical Tablets and Nutritional Supplements:
1,2-Benzenedicarboxylicacid, ion(2-) is used as a viscosity control agent in enteric-coated pharmaceutical tablets and nutritional supplements to improve their consistency and stability.
Toxicity evaluation
Phthalates exhibit different toxicity profiles regarding their
structures in the liver, kidneys, thyroid, and testes, which are
the usual organs involved in general toxicity. The mechanism
involved in hepatocarcinogenicity may be attributed to the
modulation of peroxisomal beta-oxidation, the peroxisome
proliferator-activated receptor alpha-receptor and also gap junction intercellular communication due to continue oxidative
stress and promoting cell growth.
Two possible mechanisms of action are assumed for DEHP
in testicular atrophy in rats. One may be due to decreasing zinc
markedly in the testes. DEPH might cause its toxicity on the
testis by changing expression of ZnT-1, which is a zinc transporter
in the testes. Another possible mechanism of DEHP is
associated to reduction of testosterone biosynthesis in Leydig
cells together with inhibition of follicle stimulating hormone
(FSH) in Sertoli cells. Adverse effects of phthalates like embryo
lethality and teratogenic pregnancy are not associated to
androgen receptor (lack of interaction with androgen
receptor), but may be related to endocrine disruptors in
rodents.
Check Digit Verification of cas no
The CAS Registry Mumber 3198-29-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,9 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3198-29:
(6*3)+(5*1)+(4*9)+(3*8)+(2*2)+(1*9)=96
96 % 10 = 6
So 3198-29-6 is a valid CAS Registry Number.
3198-29-6Relevant articles and documents
Chromogenic and fluorescent “turn-on” chemodosimeter for fluoride based on F?-sensitive self-immolative linker
Wang, Xin-Yu,Guan, Feng-Jie,Li, Bin,Zhang, Hua,Wu, Hong-Wei,Ji, Kai,Liu, Chuan-Xiang
, p. 211 - 214 (2016)
A new chromogenic and fluorescent “turn-on” chemodosimeter 3 was designed and synthesized by using a fluoride-sensitive self-immolative linker, in combination with the fluorescent dyes 7-hydroxy-4-trifluoromethyl coumarin. The chemodosimeter exhibited high selectivity and sensitivity toward fluoride anions through “turn-on” chromogenic and fluorogenic dual modes.
Reactions of carbonyl compounds in basic solutions. Part 33. 1 Effect of 2-trichloro-and tribromoacetyl substituents on the alkaline hydrolysis of methyl benzoate, as well as the hydrolysis of the corresponding benzoate anions and ionisation/ring-chain tautomerism of the corresponding acids
Bowden, Keith,Raja, Sivani
, p. 39 - 42 (1999)
Rate coefficients have been measured for the alkaline hydrolysis of methyl 2-trichloro-and tribromoacetylbenzoate, as well as the alkaline hydrolysis of the corresponding 2-trichloro-and tribromobenzoate anions, in 30% (v/v) dioxane-water at several temperatures. The relative rates of hydrolysis and activation parameters demonstrate relatively rapid hydrolysis via neighbouring group participation by the acyl-carbonyl group in the ester hydrolysis and slower hydrolysis via intramolecular fission of the adducts in the benzoate anion hydrolysis. The pKa values of the corresponding benzoic acids have been measured in water and their ring-chain tautomeric equilibrium constants determined.
Reactivities of Ester Radical Anions
Masnovi, John,Maticic, Jeanne
, p. 5189 - 5191 (2007/10/02)
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