319924-88-4Relevant articles and documents
One step synthesis of 2-alkenylchromanes via inverse electron-demand Hetero-Diels–Alder reaction of o-quinone methide with unactivated dienes
Liu, Jian,Wang, Xiaoxiao,Xu, Lubin,Hao, Zhihui,Wang, Liang,Xiao, Jian
supporting information, p. 7642 - 7649 (2016/11/11)
The synthetically important 2-alkenylchromane derivatives were constructed in good yields under metal-free condition via inverse electron demand Hetero-Diels–Alder reaction of o-quinone methides with unactivated dienes. This strategy features mild conditi
Synthesis of chromans via [3 + 3] cyclocoupling of phenols with allylic alcohols using a Mo/o-chloranil catalyst system
Yamamoto, Yoshihiko,Itonaga, Kouhei
supporting information; experimental part, p. 717 - 720 (2009/08/19)
(Chemical Equation Presented) The combination of a molybdenum complex (CpMoCl(CO)3 or [CpMo(CO)3]2) and o-chloranil was used as a catalyst in the [3 + 3] cyclocoupling of phenols and allylic alcohols under microwave heating conditions. Substituted chromans were selectively obtained in moderate to good isolated yields.
Inter- and intramolecular Mitsunobu reaction based approaches to 2-substituted chromans and chroman-4-ones
Hodgetts, Kevin J.
, p. 6860 - 6870 (2007/10/03)
Two approaches to optically active 2-substituted chromans and chroman-4-ones are described. The first utilized an intermolecular Mitsunobu reaction of a homochiral halopropanol and 2-bromophenol followed by cyclization to the 2-substituted chroman. In addition, a double lithiation procedure was developed to introduce additional functionality to the chroman. The second approach utilized an intramolecular Mitsunobu cyclization to give the 2-substituted chroman-4-one nucleus. The methodologies were applied to the syntheses of several biologically active natural and synthetic products.
