3201-47-6

Basic information

• Product Name: 3-phenyl-5-methoxy-1,2,4-oxadiazole
• Synonyms: 3-phenyl-5-methoxy-1,2,4-oxadiazole
• CAS NO: 3201-47-6
• Molecular Weight: 176.175
• Mol File: 3201-47-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-phenyl-5-methoxy-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-5-methoxy-1,2,4-oxadiazole(3201-47-6)
• EPA Substance Registry System: 3-phenyl-5-methoxy-1,2,4-oxadiazole(3201-47-6)

Safety Data

• Hazardous Substances Data: 3201-47-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 827-44-1 5-chloro-3-phenyl-1,2,4-oxadiazole 
• 186581-53-3 diazomethane 
• 1456-22-0 3-phenyl-1,2,4-oxadiazol-5-one 
• 58599-10-3 benzimidoylcarbamic acid methyl ester 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 1456-22-0 3-phenyl-4H-[1,2,4]oxadiazol-5-one 

Relevant articles and documents

Rh(II)-Catalyzed Transannulation of 1,2,4-Oxadiazole Derivatives with 1-Sulfonyl-1,2,3-triazoles: Regioselective Synthesis of 5-Sulfonamidoimidazoles

An effective method for the synthesis of fully substituted 5-sulfonamidoimidazoles by Rh(II)-catalyzed transannulation of 1,2,4-oxadiazole derivatives with N-sulfonyl-1,2,3-triazoles is reported. The reaction works well with both aromatic 1,2,4-oxadiazoles and 1,2,4-oxadiazol-5-ones providing a flexible approach to N-(alkoxy/amino)carbonyl- and N-alkyl-substituted imidazoles. Both the disclosed reactions are completely regioselective and provide the first examples of a carbenoid-mediated transformation of N,N,O-heterocycles.