3202-77-5

Basic information

• Product Name: 4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one
• CAS NO: 3202-77-5
• Molecular Formula: C₁₁H₁₃NO₂S
• Molecular Weight: 223.2914
• Mol File: 3202-77-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 356.2°C at 760 mmHg
• Flash Point: 169.2°C
• Density: 1.286g/cm³
• Vapor Pressure: 2.97E-05mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one(3202-77-5)
• EPA Substance Registry System: 4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one(3202-77-5)

Safety Data

• Hazardous Substances Data: 3202-77-5(Hazardous Substances Data)

Usage

General Description

The chemical compound "4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one" is a complex molecule that contains a morpholine ring, a sulfur atom, and a cyclohexadienone ring. The morpholine ring contains a nitrogen atom and a sulfur atom attached to a carbon atom, while the cyclohexadienone ring consists of a six-carbon ring with two double bonds and a ketone functional group. 4-[morpholin-4-yl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one likely possesses diverse chemical and biological properties due to the presence of the morpholine and cyclohexadienone moieties, and may have potential applications in pharmaceuticals, agrochemicals, or materials science research. Its unique structure makes it an interesting target for further study and potential applications.

Upstream product

• 1696-20-4 4-acetylmorpholine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 110-91-8 morpholine 

Downstream Products

• 1321807-47-9 4-methyl-N-((4-hydroxyphenyl)(morpholino)methylene)benzensulfonamide 
• 76226-76-1 Acetic acid 4-[morpholin-4-yl-(quinolin-2-yl-hydrazono)-methyl]-phenyl ester; hydriodide 
• 76226-65-8 4-(p-acetoxy-α-methylthiobenzylidene)morpholinium iodide 
• 76226-77-2 4-[Morpholin-4-yl-(quinolin-2-yl-hydrazono)-methyl]-phenol; hydriodide 
• 76226-61-4 p-acetoxythiobenzomorpholide 

Relevant articles and documents

Mixed bases mediated synthesis of thioamides in water

A mixed bases mediated protocol is developed to synthesize thioamides from N-aryl or N-alkylamide, aldehyde and elemental sulfur in water. This reaction requires no addition of external oxidant and avoids large excess of amides. Various functional groups

Sulfated polyborate catalyzed Kindler reaction: a rapid, efficient, and green protocol

A rapid, green, and efficient one-pot, three-component Kindler reaction was developed using a sulfated polyborate catalyst. The method described the reaction of aldehydes, amines/ammonium acetate, and sulfur for the synthesis of thioamides using sulfated polyborate under a solvent free condition at 100?°C. The key features of the present protocol are high yields, short reaction time, easy workup, and recyclability of a catalyst which gives economical as well as ecological rewards. The present method also has an ability to tolerate a variety of functional groups. Graphical abstract: [Figure not available: see fulltext.].

Willgerodt-kindler's microwave-enhanced synthesis of thioamide derivatives

The Willgerodt-Kindler reaction was applied to a series of aromatic aldehydes and ketones. The reactions were performed in a dipolar aprotic solvent (mainly DMF) in the presence of a base catalyst (4-methylmorpholine) and utilized microwave (mw) irradiation. The pulsed mw technique rather than the continuous irradiation was preferred because it limited side reactions and hydrogen sulfide production. While not always superior to the thermal activation of the reaction, the procedure involving repetitive short pulses of microwave irradiation was found to be faster and result in consistently cleaner products. The technique can be easily applied in a fast parallel synthesis process.