320574-77-4Relevant articles and documents
PROCESS FOR PREPARING 1,2,6,7-TETRAHYDRO-8H-INDENO[5,4-B]FURAN-8-ONE
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, (2011/05/05)
The invention provides a process for preparing 1,2,6,7-tetrahydro-8H-indeno-[5,4-b]furan-8-one (I), said process comprising the steps: (i) subjecting 6-hydroxy-7-allyl-indan-1-one to ozonolysis followed by reduction in the presence of methanol to form 2-methoxy-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one; (ii) subjecting 6-hydroxy-7-allyl-indan-1-one to alcohol elimination to form 6,7-dihydro-8H-indeno-[5,4-b]furan-8-one; and (iii) subjecting 6,7-dihydro-8H-indeno-[5,4-b]furan-8-one to hydrogenation to obtain 1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one.
PROCESS FOR THE PREPARATION OF RAMELTEON
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Page/Page column 17-18, (2010/10/03)
A process is described for the preparation on an industrial scale of N-[2-(8S)- 1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl] propionamide, ramelteon, having the structure illustrated below: (I).
Predicting the Claisen rearrangement regioselectivity of allylindanyl and allyltetrahydronaphthalenyl ether derivatives by 1H NMR experiments
Rodrigues, Denise C.,Fernandes, Sergio A.,Marsaioli, Anita J.
, p. 970 - 974 (2007/10/03)
The regioselectivity of the Claisen rearrangement of allylindanyl and allyltetrahydronaphthalenyl ether derivatives can be predicted by conformational preference detected by 1H NMR NOE difference spectra and T1 measurements. Copyright
