32090-98-5

Basic information

• Product Name: N-phenyl-2-fluoroacetanilide
• Synonyms: N-phenyl-2-fluoroacetanilide
• CAS NO: 32090-98-5
• Molecular Weight: 229.254
• Mol File: 32090-98-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-phenyl-2-fluoroacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-fluoroacetanilide(32090-98-5)
• EPA Substance Registry System: N-phenyl-2-fluoroacetanilide(32090-98-5)

Safety Data

• Hazardous Substances Data: 32090-98-5(Hazardous Substances Data)

Upstream product

• 1993-03-9 o-fluorophenylboronic acid 
• 1034926-54-9 bis(2-fluorophenyl)iodonium tetrafluoroborate 
• 103-84-4 Acetanilid 
• 348-54-9 2-Fluoroaniline 
• 1072-85-1 o-fluorobromobenzene 
• 108-86-1 bromobenzene 
• 399-31-5 N-(2-fluorophenyl)acetamide 

Downstream Products

• 129574-30-7 4-Chloro-1-(2-fluoro-phenyl)-3-methyl-1H-quinolin-2-one 
• 129574-30-7 4-Chloro-1-(2-fluoro-phenyl)-3-methyl-1H-quinolin-2-one 
• 129574-30-7 N-(2-fluorophenyl)-4-chloro-3-methyl-2(1H)-quinolone 
• 129574-36-3 N-(2-fluorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone 
• 328-20-1 N-(2-fluorophenyl)-N-phenylamine 

Relevant articles and documents

Metal-free n -arylation of secondary amides at room temperature

The arylation of secondary acyclic amides has been achieved with diaryliodonium salts under mild and metal-free conditions. The methodology has a wide scope, allows synthesis of tertiary amides with highly congested aryl moieties, and avoids the regioselectivity problems observed in reactions with (diacetoxyiodo)benzene.

Antiviral Compounds

Compounds and methods for preventing and treating viral infections are provided. In some embodiments, novel compounds broad-spectrum antiviral activity are provided. In more specific embodiments, the compounds and methods are effective against viruses such as Venezuelan Equine Encephalitis, West Nile Virus, and Hepatitis C.

Sterically Hindered N-Aryl-2(1H)-Quinolones and N-Aryl-6(5H)-Phenanthridinones: Separation of Enantiomers and Barriers to Racemization

The novel N-aryl-4-chloro-3-methyl-2(1H)-quinolones (1)-(4) have been synthesized by condensation of the appropriate diphenylamine with diethyl methylmalonate and subsequent chlorination of the resulting N-aryl-4-hydroxy-3-methyl-2(1H)-quinolones (7)-(10). 5-(1-Naphthyl)-6(5H)-phenanthridinone (5) has been synthesized by the Chapman rearrangement of the 6-(1-naphthoxy)phenanthridine (11).Separation of the enantiomers (M) and (P) of the quinolones (1)-(4) and phenanthridinones (5), (6) was achieved by liquid chromatography on triacetylcellulose.The barriers to partial rotation about the C-N bond in (1)-(6) were determined by thermal racemization of enantiomers and are compared with those of structurally related molecules.