321352-70-9

Basic information

• Product Name: (3-{5-amino-2-methoxy-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester
• Synonyms: (3-{5-amino-2-methoxy-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester
• CAS NO: 321352-70-9
• Molecular Weight: 425.408
• Mol File: 321352-70-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-{5-amino-2-methoxy-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-{5-amino-2-methoxy-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester(321352-70-9)
• EPA Substance Registry System: (3-{5-amino-2-methoxy-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester(321352-70-9)

Safety Data

• Hazardous Substances Data: 321352-70-9(Hazardous Substances Data)

Upstream product

• 321352-68-5 [3-(3-iodo-2-methoxy-5-nitro-phenyl)-prop-2-ynyl]-carbamic acid tert-butyl ester 
• 92136-39-5 N-tert-Butoxycarbonyl-1-amino-3-propyne 
• 31106-75-9 1-methoxy-2,6-diiodido-4-nitrobenzene 
• 14719-21-2 trifluoroacetyl-propargyl amine 
• 321352-69-6 (3-{2-methoxy-5-nitro-3-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenyl}-prop-2-ynyl)-carbamic acid tert-butyl ester 

Downstream Products

• 321352-72-1 4-{3-(3-tert-butoxycarbonylamino-prop-1-ynyl)-5-[3-(9H-fluoren-9-ylmethoxycarbonylamino)-prop-1-ynyl]-4-methoxy-phenylsulfamoyl}-3-nitro-benzoic acid 
• 321352-71-0 4-{3-(3-tert-butoxycarbonylamino-prop-1-ynyl)-4-methoxy-5-[3-(2,2,2-trifluoro-acetylamino)-prop-1-ynyl]-phenylsulfamoyl}-3-nitro-benzoic acid methyl ester 

Relevant articles and documents

A linker scaffold to present dimers of pharmacophores prepared by solid-phase syntheses

Mimicry or disruption of protein-protein interactions requires the presentation of pharmacophores to match discontinuous sites on the macromolecular surfaces. The linker shown here was designed to achieve this. The orthogonal protecting groups on the linker allow it to be differentially functionalized, then cleaved from the resin using re-agents that will not interfere with biological assays. Fmoc-9-fluorenylmethoxycarbonyl, Boc = tert-butoxycarbonyl.