321837-83-6

Basic information

• Product Name: methyl 5-((2'-tert-butyloxycarbonylamino)-L-phenylpropionyl)amino-4-oxopentanoate
• Synonyms: methyl 5-((2'-tert-butyloxycarbonylamino)-L-phenylpropionyl)amino-4-oxopentanoate
• CAS NO: 321837-83-6
• Molecular Weight: 392.452
• Mol File: 321837-83-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 5-((2'-tert-butyloxycarbonylamino)-L-phenylpropionyl)amino-4-oxopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-((2'-tert-butyloxycarbonylamino)-L-phenylpropionyl)amino-4-oxopentanoate(321837-83-6)
• EPA Substance Registry System: methyl 5-((2'-tert-butyloxycarbonylamino)-L-phenylpropionyl)amino-4-oxopentanoate(321837-83-6)

Safety Data

• Hazardous Substances Data: 321837-83-6(Hazardous Substances Data)

Upstream product

• 79416-27-6 methyl aminolevulinate 
• 3674-06-4 Boc-Phe-ONSu 
• 5451-09-2 5-aminolevulinic acid hydrochloride 
• 186581-53-3 diazomethane 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Relevant articles and documents

Ethylene glycol and amino acid derivatives of 5-aminolevulinic acid as new photosensitizing precursors of Protoporphyrin IX in cells

Protoporphyrin IX (PpIX) is used as a photosensitizing agent in photodynamic detection and therapy (PDT) of cancer and is synthesized intracellularly from aminolevulinic acid (ALA) precursors. To evaluate means to specifically target ALA derivatives to de

Improved peptide prodrugs of 5-ALA for PDT: Rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization

Twenty-seven dipeptide derivatives of general structure Ac-Xaa-ALA-OR were synthesized as potential prodrugs for 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT). Xaa is an R-amino acid, chosen to provide a prodrug with appropriately tailored l