321970-54-1Relevant articles and documents
Design and synthesis of novel diamide derivatives of glycine as antihyperglycemic agents
Sharma, Radhika,Soman, Shubhangi S.
supporting information, p. 1307 - 1317 (2016/08/16)
DPP-4 inhibition is one of the most extensively explored approaches for the management of type 2 diabetes (T2D). Most DPP-4 inhibitors in the market contain a proline mimetic active pharmacophore. Herein, we report the design, synthesis, and preliminary e
N-substituted piperidines and their use as pharrmaceuticals
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Page/Page column 18, (2010/02/15)
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.