322-46-3Relevant articles and documents
SYNTHESIS AND ANTITUMOR ACTION OF SOME PYRIDOPYRAZINES
Postovskii, I. Ya.,Charushin, V. N.,Mokrushina, G. A.,Kotovskaya, S. K.,Barybin, A. S.,et al.
, p. 824 - 826 (1982)
-
Reduction of different electron-poor N-heteroarylhydrazines in strong basic conditions
Unciti-Broceta, Asier,Pineda De Las Infantas, Maria J.,Gallo, Miguel A.,Espinosa, Antonio
, p. 1754 - 1762 (2008/02/03)
The first application of the Wolff-Kishner reduction methodology to electron-poor heteroaromatic compounds is reported. Hydrazino-containing heterocycles with hydrazone-type tautomery have been reduced under basic conditions. This novel chemistry was successfully applied to mono-dehalogenate a number of electron-poor heterocycles in a regioselective manner. According to the experimental results, this reductive process is a base-catalyzed reaction that takes only place in the presence of air, probably through an oxygen-assisted mechanism. As consequence of the specific features of this kind of hydrazone/enehydrazine tautomers, the overall outcome of the process is the synthesis of a Shapirotype reduction product by simply using a milder version of the Huang-Minlon methodology.
2,3-Dihydroxy-1,4-dioxane: A Stable Synthetic Equivalent of Anhydrous Glyoxal
Venuti, Michael C.
, p. 61 - 63 (2007/10/02)
-
